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histamine antagonist
Sign in to saveAlso known as antihistamine, histamine inhibitor, histamine antagonists
Antihistamines are drugs that treat hay fever and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. Antihistamines are usually for short-term treatment. Chronic allergies increase the risk of health problems which antihistamines might not treat, including asthma, sinusitis, and lower respiratory tract infection. Consultation of a medical professional is recommended for t
Key facts
- Drug class.Name
- Antihistamine
- Drug class.Image
- Histamine.svg
- Drug class.ImageClass
- skin-invert-image
- Drug class.Alt
- Histamine structure diagram
- Drug class.Caption
- Histamine structure
- Drug class.ATC_prefix
- R06
- Drug class.Biological_target
- Histamine receptorsHRH1HRH2HRH3HRH4
- Drug class.Mechanism_of_action
- Receptor antagonistInverse agonist
- Drug class.MeshID
- D006633
via Wikipedia infobox
Research
77,558 papers- Histamine receptors and COVID-19.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2021
- Molecular determinants of selective agonist and antagonist binding to the histamine H₄ receptor.Current topics in medicinal chemistry · 2011
- The histamine H3R and dopamine D2R/D3R antagonist ST-713 ameliorates autism-like behavioral features in BTBR T+tf/J mice by multiple actions.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
- Antihistamines and itch.Handbook of experimental pharmacology · 2015
- Label-free cell phenotypic profiling of histamine H4R receptor and discovery of non-competitive H4R antagonist from natural products.Bioorganic chemistry · 2024
via PubMed
Wikidata facts
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- topic's main category
- Category:Antihistamines
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- Antihistamines
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Encyclopedic overview
18 sectionsContents
- Medical uses
- Types
- H<sub>1</sub>-antihistamines
- List of H<sub>1</sub> antagonists/inverse agonists
- H<sub>2</sub>-antihistamines
- H<sub>3</sub>-antihistamines
- <span class="anchor" id="H4-receptor antagonists"></span> H<sub>4</sub>-antihistamines <!-- [[H4 antagonist]] redirects here -->
- Atypical antihistamines
- Histidine decarboxylase inhibitors
- Mast cell stabilizers
- History
- Society and culture
- Research
- Special populations
- Potential uses studied
- See also
- References
- External links
Antihistamines are drugs that treat hay fever and other allergies. Typically, people take antihistamines as an inexpensive, generic (not patented) drug that can be bought without a prescription and provides relief from nasal congestion, sneezing, or hives caused by pollen, dust mites, or animal allergy with few side effects. Antihistamines are usually for short-term treatment. Chronic allergies increase the risk of health problems which antihistamines might not treat, including asthma, sinusitis, and lower respiratory tract infection. Consultation of a medical professional is recommended for those who intend to take antihistamines for longer-term use.
Although the general public typically uses the word "antihistamine" to describe drugs for treating allergies, physicians and scientists use the term to describe a class of drug that opposes the activity of histamine receptors in the body. In this sense of the word, antihistamines are subclassified according to the histamine receptor that they act upon. The two largest classes of antihistamines are H1-antihistamines and H2-antihistamines.
Excerpted from Wikipedia’s “histamine antagonist” article, available under the CC BY-SA 4.0 licence.