fluacizine
Sign in to saveFluacizine, sold under the brand name Phtorazisin, is a tricyclic antidepressant (TCA) of the phenothiazine group which is or was marketed in Russia. Unlike other phenothiazines, fluacizine is not an antipsychotic, and can actually reverse catalepsy and extrapyramidal symptoms induced by antidopaminergic agents like antipsychotics, reserpine, and tetrabenazine as well as potentiate amphetamine-induced stereotypy. It is known to act as a norepinephrine reuptake inhibitor, antihistamine, and anticholinergic. The drug was developed in the 1960s and was marketed in the 1970s. It is the trifluorome
In the Vinony graph
Within Vinony's link graph, fluacizine is referenced by 448 other articles, and connects out to atropine, histamine antagonist and tricyclic antidepressant.
Vinony files it under Abandoned drugs, Antidepressants and Carboxamides.
Its subject is documented across 6 Wikipedia language editions.
Wikidata facts
- Mass
- 394.133
Show 3 more facts
- chemical formula
- C₂₀H₂₁F₃N₂OS
- Commons category
- Fluacizine
- canonical SMILES
- CCN(CC)CCC(=O)N1C2=CC=CC=C2SC3=C1C=C(C=C3)C(F)(F)F
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Fluacizine, sold under the brand name Phtorazisin, is a tricyclic antidepressant (TCA) of the phenothiazine group which is or was marketed in Russia. Unlike other phenothiazines, fluacizine is not an antipsychotic, and can actually reverse catalepsy and extrapyramidal symptoms induced by antidopaminergic agents like antipsychotics, reserpine, and tetrabenazine as well as potentiate amphetamine-induced stereotypy. It is known to act as a norepinephrine reuptake inhibitor, antihistamine, and anticholinergic. The drug was developed in the 1960s and was marketed in the 1970s. It is the trifluoromethyl analogue of chloracizine.
==See also== Pipofezine List of Russian drugs
Excerpted from Wikipedia’s “fluacizine” article, available under the CC BY-SA 4.0 licence.