(RS)-mianserin

Mianserin, sold as Tolvon and other brand names, is an atypical antidepressant used primarily for treating depression in Europe and other countries. It is a tetracyclic antidepressant (TeCA) and is closely related to mirtazapine in terms of chemical structure, actions, and effects, although mianserin has greater noradrenergic activity and less 5-HT3 receptor antagonism.

==Medical uses== Mianserin is used at higher doses (30–90 mg/day) for the treatment of major depressive disorder. At lower doses (around 10 mg/day), it is used to treat insomnia.