chlorpromazine
Sign in to saveChlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar disorder, severe behavioral problems in children including those with attention deficit hyperactivity disorder, nausea and vomiting, anxiety before surgery, and hiccups that do not improve following other measures. It can be given orally (by mouth), by intramuscular injection (injection into a muscle), or intravenously (injection into a vein).
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 443519547
- Drug.image
- Chlorpromazine.svg
- Drug.image_class
- skin-invert-image
- Drug.alt
- Skeletal formula of chlorpromazine
- Drug.width
- 222
- Drug.image2
- Chlorpromazine-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.alt2
- Ball-and-stick model of the chlorpromazine molecule
- Drug.tradename
- Thorazine, Largactil, others
- Drug.MedlinePlus
- a682040
- Drug.DailyMedID
- Chlorpromazine
- Drug.pregnancy_AU
- C
- Drug.routes_of_administration
- By mouth, rectal, intramuscular, intravenous
- Drug.class
- Typical antipsychotic
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- AA01
- Drug.legal_AU
- S4
via Wikipedia infobox
Research
22,043 papers- Chlorpromazine versus placebo for schizophrenia.The Cochrane database of systematic reviews · 2000
- Chlorpromazine versus placebo for schizophrenia.The Cochrane database of systematic reviews · 2014
- Chlorpromazine versus placebo for schizophrenia.The Cochrane database of systematic reviews · 2003
- Chlorpromazine versus placebo for schizophrenia.The Cochrane database of systematic reviews · 2007
- Chlorpromazine's impact on Mytilus galloprovincialis: a multi-faceted investigation.Chemosphere · 2024
via PubMed
Article
16 sectionsContents
- Medical uses
- Other uses
- Contraindications
- Adverse effects
- Discontinuation
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- History
- Society and culture
- In literature
- Names
- Research
- Veterinary use
- References
Chlorpromazine (CPZ), marketed under the brand names Thorazine and Largactil among others, is an antipsychotic medication. It is primarily used to treat psychotic disorders such as schizophrenia. Other uses include the treatment of bipolar disorder, severe behavioral problems in children including those with attention deficit hyperactivity disorder, nausea and vomiting, anxiety before surgery, and hiccups that do not improve following other measures. It can be given orally (by mouth), by intramuscular injection (injection into a muscle), or intravenously (injection into a vein).
Chlorpromazine is in the typical antipsychotic class, and, chemically, is one of the phenothiazines. Its mechanism of action is not entirely clear but is believed to be related to its ability as a dopamine antagonist. It has antiserotonergic and antihistaminergic properties.
Gallery (4)
Connections
Categories
Alpha-1 blockersAlpha-2 blockersAntiaggressive drugsAntiemeticsChemicals using indexlabelsChloroarenesCleanup tagged articles with a reason field from January 2022CYP2D6 inhibitorsDimethylamino compoundsDrugboxes which contain changes to watched fieldsDrugs with non-standard legal statusECHA InfoCard ID from Wikidata