HOXA11
Sign in to saveAlso known as HOX1, HOX1I, RUSAT1, homeobox A11
Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene.
Gene data
HOXA11- Name
- homeobox A11
- Type
- protein-coding
- Position
- 27,181,157–27,185,253 (−)
- Aliases
- HOX1, HOX1I, RUSAT1
- Ensembl
- ENSG00000005073
- RefSeq RNA
- NM_005523.6
- RefSeq protein
- NP_005514.1
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
homeobox A11
- Symbol
- HOXA11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:27,181,157-27,185,253
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Homeobox protein Hox-A11 is a protein that in humans is encoded by the HOXA11 gene.
== Function ==
Excerpted from Wikipedia’s “HOXA11” article, available under the CC BY-SA 4.0 licence.