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GeneQ18027147· pop 6· linked from 823 articles

HOXA13

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Also known as HOX1, HOX1J, homeobox A13

Homeobox protein Hox-A13 is a protein that in humans is encoded by the HOXA13 gene.

In the Vinony graph

Within Vinony's link graph, HOXA13 is referenced by 823 other articles, and connects out to Q180686, human chromosome 7 and Ensembl genome database project.

Vinony files it under Genes on human chromosome 7 and Transcription factors.

Its subject is documented across 6 Wikipedia language editions.

Gene data

HOXA13

Name: homeobox A13
Type: protein-coding
Position: 27,193,503–27,200,091 (−)
Aliases: HOX1, HOX1J
Ensembl: ENSG00000106031
RefSeq RNA: NM_000522.5
RefSeq protein: NP_000513.2

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

skeletal system development regulation of DNA-templated transcription regulation of transcription by RNA polymerase II prostate gland development response to testosterone positive regulation of transcription by RNA polymerase II embryonic hindgut morphogenesis

Molecular function

transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific

Cellular component

chromatin nucleus nucleus nucleoplasm

via MyGene.info

Gene · Ensembl

homeobox A13

Symbol: HOXA13
Biotype: Protein coding
Organism: Homo sapiens
Location: 7:27,193,503-27,200,091
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 73882
exact match: identifiers.org/ncbigene/3209
genomic start: 27233122
genomic end: 27200091
cytogenetic location: 7p15.2

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections

Contents

Function
Clinical significance
See also
References
Further reading
External links

Homeobox protein Hox-A13 is a protein that in humans is encoded by the HOXA13 gene.

== Function ==

Excerpted from Wikipedia’s “HOXA13” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 7 Transcription factors