File:Hydrochinon2.svg · Wikimedia Commons · See Wikimedia Commons
hydroquinone
Sign in to saveAlso known as p-hydroxyphenol, 1,4-dihydroxybenzene, benzene-1,4-diol, quinol, 1,4-benzenediol, p-benzenediol, dihydroxybenzene, p-hydroquinone
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones. The name "hydroquinone" was coined by Friedrich Wöhler in 1843.
Chemical data
- Formula
- C6H6O2
- Molecular weight
- 110.11 g/mol
- IUPAC name
- benzene-1,4-diol
- SMILES
- C1=CC(=CC=C1O)O
- InChIKey
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N
- XLogP
- 0.6
- Polar surface area
- 40.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Research
10,020 papers- An update on the safety of hydroquinone.Archives of dermatological research · 2024
- Hydroquinone: myths and reality.Clinical and experimental dermatology · 2021
- Hydroquinone.IARC monographs on the evaluation of carcinogenic risks to humans · 1999
- Hyperpigmentation: Looking beyond hydroquinone.Journal of cosmetic dermatology · 2022
- The effectiveness and safety of 3% tranexamic acid cream vs. 4% hydroquinone cream for mixed-type melasma in skin of color: a double-blind, split-face, randomized controlled trial.Acta dermatovenerologica Alpina, Pannonica, et Adriatica · 2024
via PubMed
Wikidata facts
- Mass
- 110.037
- Image
- Hydroquinone crystal.jpg
Show 14 more facts
- chemical formula
- C₆H₆O₂
- Commons category
- Hydroquinone
- NIOSH Pocket Guide ID
- 0338
- density
- 1.33
- immediately dangerous to life or health
- 50
- melting point
- 172.3
- boiling point
- 286
- flash point
- 329
- solubility
- 7
- ionization energy
- 7.95
- vapor pressure
- 0.00001
- time-weighted average exposure limit
- 2
- ceiling exposure limit
- 2
- canonical SMILES
- C1=CC(=CC=C1O)O
Sources (7)
via Wikidata · CC0
~9 min read
Article
9 sectionsContents
- Production
- Reactions
- Redox
- Amination
- Uses
- Skin depigmentation
- Natural occurrences
- References
- External links
Hydroquinone, also known as benzene-1,4-diol or quinol, is an aromatic organic compound that is a type of phenol, a derivative of benzene, having the chemical formula C6H4(OH)2. It has two hydroxyl groups bonded to a benzene ring in a para position. It is a white granular solid. Substituted derivatives of this parent compound are also referred to as hydroquinones. The name "hydroquinone" was coined by Friedrich Wöhler in 1843.
In 2023, it was the 274th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.