hydroxymethylglutaryl-CoA synthase
Sign in to saveAlso known as hydroxymethylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl coenzyme A synthase, 3-hydroxy-3-methylglutaryl-CoA synthase, acetoacetyl coenzyme A transacetase, (S)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA-acetylating), acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming), (s)-3-hydroxy-3-methylglutaryl-CoA acetoacetyl-CoA-lyase (CoA- acetylating), hydroxymethylglutaryl coenzyme alpha-condensing enzyme
class of enzymes
Research
1,803 papers- Epigenetic inactivation of hydroxymethylglutaryl CoA synthase reduces ketogenesis and facilitates tumor cell motility in clear cell renal carcinoma.Pathology, research and practice · 2021
- mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway.Molecular cell · 2024
- Regulation of the mevalonate pathway.Nature · 1990
- Hmgcs2-mediated ketogenesis modulates high-fat diet-induced hepatosteatosis.Molecular metabolism · 2022
- Impaired ketogenesis in Leydig Cells drives testicular aging.Nature communications · 2025
via PubMed
Wikidata facts
Show 2 more facts
- EC enzyme number
- 2.3.3.10
- Commons category
- Hydroxymethylglutaryl-CoA synthases
Sources (1)
via Wikidata · CC0