hiperparatiroidismo

Also known as Hyperparathyroidism, hyperparathyreosis

Hyperparathyroidism is an increase in parathyroid hormone (PTH) levels in the blood. This occurs from a disorder either within the parathyroid glands (primary hyperparathyroidism) or as response to external stimuli (secondary hyperparathyroidism). Symptoms of hyperparathyroidism are caused by inappropriately elevated blood calcium excreted from the bones into the blood stream in response to increased production of parathyroid hormone. In healthy people, when blood calcium levels are high, parathyroid hormone levels should be low. With long-standing hyperparathyroidism, the most common symptom

Key facts

Medical condition.name: Hyperparathyroidism
Medical condition.image: 3D Medical Animation still shot Hyperparathyroidism.jpg
Medical condition.caption: 3D diagram of hyperparathyroidism
Medical condition.field: Endocrinology
Medical condition.symptoms: None, kidney stones, weakness, depression, bone pains, confusion, increased urination
Medical condition.complications: Osteoporosis
Medical condition.onset: 50 to 60
Medical condition.types: Primary, secondary
Medical condition.causes: Primary: parathyroid adenoma, multiple benign tumors, parathyroid cancerSecondary: vitamin D deficiency, chronic kidney disease, low blood calcium
Medical condition.diagnosis: High blood calcium and high PTH levels
Medical condition.treatment: Monitoring, surgery, intravenous normal saline, cinacalcet
Medical condition.frequency: ~2 per 1,000

via Wikipedia infobox

Research

36,939 papers

Renal hyperparathyroidism.Vitamins and hormones · 2022
Laboratory screening for hyperparathyroidism.Clinica chimica acta; international journal of clinical chemistry · 2005
Primary hyperparathyroidism and familial hyperparathyroid syndromes.Australian family physician · 2007
Sporadic and hereditary primary hyperparathyroidism.Journal of endocrinological investigation · 2011
Diagnosis of hyperparathyroidism.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 1985

via PubMed

Wikidata facts

Subclass of: disease
Image: Illu thyroid parathyroid.jpg

Show 8 more facts

NCI Thesaurus ID: C48259
Commons category: Hyperparathyroidism
health specialty: endocrinology
drug or therapy used for treatment: denosumab
exact match: www.orpha.net/ORDO/Orphanet_99879
ICD-9-CM: 252.0
genetic association: CDC73
on focus list of Wikimedia project: WikiProject Medicine

Sources (4)

via Wikidata · CC0

Article · Português

Hiperparatiroidismo é uma doença caracterizada pelo excessivo funcionamento das glândulas , causando aumento da produção do hormônio paratireóidico / hormona paratiroideia (PTH) na circulação. Pode ser classificado como primário e secundário. Hiperparatiroidismo primário leva a sinais e sintomas decorrentes do aumento de cálcio no sangue (hipercalcemia), na urina (hipercalciúria), perda óssea de cálcio e pedras nos rins (cálculo renal). Pode ser provocada por tumores benignos (adenomas), hiperplasia ou muito raramente por tumores malignos na tiróide. No Brasil atinge 0,1% da população e ocorre mais freqüentemente nas mulheres na proporção de 3 para 1, sendo mais comum após os 60 anos. Hiperparatiroidismo secundário é relacionado a perda da função renal, ao contrário do hiperparatiroidismo primário, não cursa com aumento do cálcio, se relaciona em alguns casos até com hipocalcemia, e com consequente hiperfosfatemia. A perda de massa óssea também está presente. Nos dois casos, o hiperparatiroidismo grave pode evoluir com tumor marrom e calcificação vascular, lesão óssea identificada no raio X do osso acometido, que pode ser qualquer osso do corpo.

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