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超敏反應
Sign in to saveAlso known as hypersensitivity reaction disease, GO:0002524
Hypersensitivity (also called hypersensitivity reaction) is an immune response characterized by mechanisms that cause significant tissue damage or physiological dysfunction, whether directed against pathogens, harmless environmental antigens, or self-antigens that is reproducible upon re-exposure to the antigen. While hypersensitivity mechanisms can sometimes serve protective functions (such as control of infectious diseases), they are distinguished by their capacity to cause collateral tissue damage that may exceed any protective benefit. Collectively, hypersensitivities are extremely common:
Key facts
- Medical condition.name
- Hypersensitivity
- Medical condition.image
- 2228 Immune Hypersensitivity new.jpg
- Medical condition.caption
- Types of hypersensitivity reactions
- Medical condition.field
- Immunology
via Wikipedia infobox
Research
476,942 papers- Allergy, Anaphylaxis, and Nonallergic Hypersensitivity: IgE, Mast Cells, and Beyond.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
- Food hypersensitivity.The Veterinary clinics of North America. Small animal practice · 1988
- Multiple drug hypersensitivity syndrome.Current opinion in allergy and clinical immunology · 2013
- [HYPERSENSITIVITY PNEUMONITIS].Arerugi = [Allergy] · 2020
- Systematic Review of Hypersensitivity to Parenteral Nutrition.JPEN. Journal of parenteral and enteral nutrition · 2018
via PubMed
Wikidata facts
- Subclass of
- disease
- Image
- 2228 Immune Hypersensitivity new.jpg
Show 11 more facts
- has effect
- Kounis syndrome
- exact match
- purl.obolibrary.org/obo/DOID_0060056
- topic's main category
- Category:Hypersensitivity
- health specialty
- immunology
- permanent duplicated item
- allergy
- drug or therapy used for treatment
- prednisolone
- topic has template
- Template:Hypersensitivity disease by cause
- NCI Thesaurus ID
- C3114
- risk factor
- smoking
- Commons category
- Hypersensitivity
- on focus list of Wikimedia project
- WikiProject Medicine
Sources (2)
via Wikidata · CC0
Article · 中文
超敏反應(英語:Hypersensitivity),在台灣也常稱過敏反應,是機體免疫系統受到特定抗原持續刺激,或同一抗原再次刺激的病理性過度反應,其造成機體組織發炎、損傷且功能紊亂,包括過敏(allergy)、自體免疫兩大類。 在一般情況下,機體超敏反應產生的作用分子只產生輕微症狀或局部性發炎反應,且多為IgE抗體;但在特殊的狀況下,發炎反應可能導致嚴重組織傷害甚至死亡。過敏症狀可由體液性或細胞媒介免疫反應中發展出來。體液性的超敏反應:由抗體或抗原-抗體複合物所啟動,而特別的媒介物: IgE 、IgM 、IgG 或補體等,可調節超敏反應,使敏感宿主在意外接觸抗原後數分鐘或數小時內就產生臨床症狀,最明顯的例子是立即性過敏反應;TDTH細胞媒介型過敏反應:延遲性超敏反應(delayed-type hypersensitivity、DTH),是屬於細胞性調節的反應,為一種宿主接觸抗原數天之後所產生的延遲性症狀。延遲性超敏反應是提供對抗細胞內病原體(intracellular pathogen)的重要防禦陣線,但是它們有時會導致嚴重的組織傷害。
Abstract from DBpedia / Wikipedia · CC BY-SA