IBSP

Name

integrin binding sialoprotein

Type

protein-coding

Position

87,799,546–87,813,329 (+)

Aliases

BNSP, BSP, BSP II, BSP-II, SP-II

Ensembl

ENSG00000029559

RefSeq RNA

NM_004967.4

RefSeq protein

NP_004958.2

The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

integrin binding sialoprotein

Symbol

IBSP

Biotype

Protein coding

Organism

Homo sapiens

Location

4:87,799,546-87,813,329

Strand

Forward (+)

Assembly

GRCh38