IMMT
Sign in to saveAlso known as HMP, MINOS2, P87, P87/89, P89, PIG52, Mic60, PIG4
Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene.)
Gene data
IMMT- Name
- inner membrane mitochondrial protein
- Type
- protein-coding
- Position
- 86,142,798–86,195,626 (−)
- Aliases
- HMP, MICOS60, MINOS2, Mic60, P87, P87/89, P89, PIG4, PIG52
- Ensembl
- ENSG00000132305
- RefSeq RNA
- NM_001100169.2, NM_001100170.2, NM_001400086.1, NM_001400087.1, NM_001400088.1
- RefSeq protein
- NP_001093639.1, NP_001093640.1, NP_001387015.1, NP_001387016.1, NP_001387017.1
Enables RNA binding activity. Involved in cristae formation. Located in mitochondrial inner membrane. Part of MICOS complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 38234
- exact match
- identifiers.org/ncbigene/10989
- genomic end
- 86195472
- genomic start
- 86371055
- cytogenetic location
- 2p11.2|2
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Article
6 sectionsContents
- Function
- Interactions
- Localisation/Import
- Interactions
- References
- Further reading
Mitochondrial inner membrane protein is a protein that in humans is encoded by the IMMT gene.)
IMMT encodes an inner mitochondrial membrane (IMM) protein in the nucleus. It is posttranslational transported to the IMM. Mic60/Mitofilin (encoded by the IMMT gene) is a core subunit of the MICOS-complex, directly located next to cristae junctions (CJ). Human Mic60 exists in two isoforms of different size, anchored to the IMM via its N-terminus, while most of the protein is located to the inner mitochondrial space (IMS).