IRF5
Sign in to saveAlso known as SLEB10, interferon regulatory factor 5
Interferon regulatory factor 5 is a protein that in humans is encoded by the IRF5 gene. The IRF family is a group of transcription factors that are involved in signaling for virus responses in mammals along with regulation of certain cellular functions.
Gene data
IRF5- Name
- interferon regulatory factor 5
- Type
- protein-coding
- Aliases
- SLEB10
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Dec 2016].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 8088
- exact match
- identifiers.org/ncbigene/3663
- genomic end
- 128950038
- genomic start
- 128937457
- cytogenetic location
- 7q32.1
via Wikidata · CC0
~2 min read
Article
7 sectionsContents
- Function
- Clinical significance
- Signaling
- See also
- References
- Further reading
- External links
Interferon regulatory factor 5 is a protein that in humans is encoded by the IRF5 gene. The IRF family is a group of transcription factors that are involved in signaling for virus responses in mammals along with regulation of certain cellular functions.
== Function ==