IRX3
Sign in to saveAlso known as IRX-1, IRXB1, iroquois homeobox 3
Iroquois-class homeodomain protein IRX-3, also known as Iroquois homeobox protein 3, is a protein that in humans is encoded by the IRX3 gene.
Gene data
IRX3- Name
- iroquois homeobox 3
- Type
- protein-coding
- Position
- 54,283,281–54,287,469 (−)
- Aliases
- IRX-1, IRXB1
- Ensembl
- ENSG00000177508
- RefSeq RNA
- NM_024336.3, XM_005256139.4, XM_054313909.1
- RefSeq protein
- NP_077312.2, XP_005256196.1, XP_054169884.1
IRX3 is a member of the Iroquois homeobox gene family (see IRX1; MIM 606197) and plays a role in an early step of neural development (Bellefroid et al., 1998 [PubMed 9427753]). Members of this family appear to play multiple roles during pattern formation of vertebrate embryos (Lewis et al., 1999 [PubMed 10370142]).[supplied by OMIM, Aug 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
iroquois homeobox 3
- Symbol
- IRX3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:54,283,281-54,287,469
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7385
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79191
- genomic end
- 54286787
- genomic start
- 54317216
- chromosome
- human chromosome 16
- cytogenetic location
- 16q12.2
Sources (4)
via Wikidata · CC0
~4 min read
Encyclopedic overview
7 sectionsContents
- Discovery and name
- Function
- Clinical significance
- Association with obesity
- Aberrant expression in acute leukaemia
- References
- Further reading
Iroquois-class homeodomain protein IRX-3, also known as Iroquois homeobox protein 3, is a protein that in humans is encoded by the IRX3 gene.
== Discovery and name ==
Excerpted from Wikipedia’s “IRX3” article, available under the CC BY-SA 4.0 licence.