JUND

Also known as AP-1, JunD proto-oncogene, AP-1 transcription factor subunit

gene umano

Gene data

JUND

Name: JunD proto-oncogene, AP-1 transcription factor subunit
Type: protein-coding
Position: 18,279,694–18,281,622 (−)
Aliases: AP-1
Ensembl: ENSG00000130522
RefSeq RNA: NM_001286968.2, NM_005354.6
RefSeq protein: NP_001273897.1, NP_005345.3

The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. This protein has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216). [provided by RefSeq, Nov 2013].

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II circadian rhythm response to cold response to water deprivation

Molecular function

transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription coregulator binding DNA-binding transcription activator activity, RNA polymerase II-specific

Cellular component

chromatin chromatin nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex

Pathways

MAPK signaling pathway - Homo sapiens (human)Osteoclast differentiation - Homo sapiens (human)IL-17 signaling pathway - Homo sapiens (human)Parathyroid hormone synthesis, secretion and action - Homo sapiens (human)Adaptive Immune System Adaptive Immune System Signal Transduction Signal Transduction Signaling by NTRKs Signaling by NTRKs

via MyGene.info

Gene · Ensembl

JunD proto-oncogene, AP-1 transcription factor subunit

Symbol: JUND
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:18,279,694-18,281,622
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: JUND protein.png

Show 8 more facts

HomoloGene ID: 3910
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/3727
genomic end: 18392432
genomic start: 18279694
chromosome: human chromosome 19
cytogenetic location: 19p13.11
expressed in: Brodmann area 10

Sources (4)

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via Wikidata sitelinks · CC0

JUND

Gene data

Gene Ontology

Pathways

Gene · Ensembl

Wikidata facts

Available in 5 languages

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