dextroamphetamine

Also known as Dexedrine, Dextrostat, (+)-alpha-Methylphenylethylamine, (S)-(+)-beta-Phenylisopropylamine, (S)-1-Phenyl-2-propylamine, dexamphetamine, (AlphaS)-alpha-methylbenzeneethanamine, (+)-(S)-amphetamine

Dextroamphetamine is a central nervous system (CNS) stimulant and enantiomer of amphetamine that is used in the treatment of attention deficit hyperactivity disorder (ADHD) and narcolepsy. It is also used illicitly to enhance cognitive and athletic performance, and recreationally as an aphrodisiac and euphoriant. Dextroamphetamine is generally regarded as the prototypical stimulant.

Key facts

Drug.chirality: Dextrorotatory enantiomer
Drug.SMILES: C[C@@H](Cc1ccccc1)N
Drug.StdInChI: 1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1
Drug.StdInChIKey: KWTSXDURSIMDCE-QMMMGPOBSA-N
Drug.density: 0.913
Drug.boiling_point: 201.5
Drug.solubility: 20
Drug.sol_units: mg per ml
Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 596899008
Drug.INN: Dexamfetamine
Drug.image

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Article

26 sections

Contents

Uses
Medical
ADHD
Narcolepsy
Enhancing performance
Recreational
Contraindications
Adverse effects
Overdose
Interactions
Pharmacology
Pharmacodynamics
Related endogenous compounds
Pharmacokinetics
History, society, and culture
Formulations
Transdermal dextroamphetamine patches
Dextroamphetamine sulfate
Lisdexamfetamine
Adderall
Research
Schizophrenia
Notes
Reference notes
References
External links

The amphetamine molecule exists as two enantiomers, levoamphetamine and dextroamphetamine. Dextroamphetamine is the dextrorotatory, or 'right-handed', enantiomer and exhibits more pronounced effects on the central nervous system than levoamphetamine. Pharmaceutical dextroamphetamine sulfate is available as both a brand name and generic drug in a variety of dosage forms. Dextroamphetamine is sometimes prescribed as the inactive prodrug lisdexamfetamine.