Structure via PubChem · Public domain (PubChem)
JWH-251
Sign in to saveAlso known as 1-pentyl-3-(2-methylphenylacetyl)indole
JWH-251 (1-pentyl-3-(2-methylphenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about five times selectivity for CB1 with a Ki of 29 nM and 146 nM at CB2. Similar to the related 2'-methoxy compound JWH-250, the 2'-chloro compound JWH-203, and the 2'-bromo compound JWH-249, JWH-251 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.
In the Vinony graph
Within Vinony's link graph, JWH-251 is referenced by 455 other articles, and connects out to cannabinoids, synthetic cannabinoid and synhexyl.
Vinony files it under CB1 receptor agonists, CB2 receptor agonists and Designer drugs.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C22H25NO
- Molecular weight
- 319.4 g/mol
- IUPAC name
- 2-(2-methylphenyl)-1-(1-pentylindol-3-yl)ethanone
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 319.194
Show 3 more facts
- chemical formula
- C₂₂H₂₅NO
- canonical SMILES
- CCCCCN1C=C(C2=CC=CC=C21)C(=O)CC3=CC=CC=C3C
- Commons category
- JWH-251
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
JWH-251 (1-pentyl-3-(2-methylphenylacetyl)indole) is a synthetic cannabinoid from the phenylacetylindole family, which acts as a cannabinoid agonist with about five times selectivity for CB1 with a Ki of 29 nM and 146 nM at CB2. Similar to the related 2'-methoxy compound JWH-250, the 2'-chloro compound JWH-203, and the 2'-bromo compound JWH-249, JWH-251 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds.
In the United States, all CB1 receptor agonists of the 3-phenylacetylindole class such as JWH-251 are Schedule I Controlled Substances.
Excerpted from Wikipedia’s “JWH-251” article, available under the CC BY-SA 4.0 licence.