Structure via PubChem · Public domain (PubChem)
kaempferide
Sign in to saveAlso known as Kaempferol 4'-methyl ether, Campheride, 4'-O-Methylkaempferol, 1.3,5,7-Trihydroxy-2-(4-methoxyphenyl)-4-benzopyrone
Kaempferide is an O-methylated flavonol, a type of chemical compound. It can be found in Kaempferia galanga (aromatic ginger). It has been noted to inhibit pancreatic cancer growth by blockading an EGFR-related pathway.
Chemical data
- Formula
- C16H12O6
- Molecular weight
- 300.26 g/mol
- IUPAC name
- 3,5,7-trihydroxy-2-(4-methoxyphenyl)chromen-4-one
- SMILES
- COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
- InChIKey
- SQFSKOYWJBQGKQ-UHFFFAOYSA-N
- XLogP
- 2.2
- Polar surface area
- 96.2 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- flavone
- Mass
- 300.063388
Show 4 more facts
- found in taxon
- Cota altissima
- canonical SMILES
- COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
- chemical formula
- C₁₆H₁₂O₆
- Commons category
- Kaempferid
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Metabolism
- Glycosides
- References
- External links
Kaempferide is an O-methylated flavonol, a type of chemical compound. It can be found in Kaempferia galanga (aromatic ginger). It has been noted to inhibit pancreatic cancer growth by blockading an EGFR-related pathway.
== Metabolism == The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adenosyl-L-homocysteine and kaempferide.
Excerpted from Wikipedia’s “kaempferide” article, available under the CC BY-SA 4.0 licence.