Structure via PubChem · Public domain (PubChem)
fisetin
Sign in to saveAlso known as 3,7,3',4'-TETRAHYDROXYFLAVONE
Fisetin (7,3′,4′-flavon-3-ol) is a plant flavonol from the flavonoid group of polyphenols. It occurs in many plants where it serves as a yellow pigment. It is found in many fruits and vegetables, such as strawberries, apples, persimmons, onions, and cucumbers.
Chemical data
- Formula
- C15H10O6
- Molecular weight
- 286.24 g/mol
- IUPAC name
- 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
- SMILES
- C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
- InChIKey
- XHEFDIBZLJXQHF-UHFFFAOYSA-N
- XLogP
- 2
- Polar surface area
- 107 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- osteoarthritis, knee, severe acute respiratory syndrome, childhood cancer, COVID-19
via ChEMBL · EBI
Research
1,611 papers- Fisetin as a senotherapeutic agent: Evidence and perspectives for age-related diseases.Mechanisms of ageing and development · 2024
- Fisetin is a senotherapeutic that extends health and lifespan.EBioMedicine · 2018
- Fisetin ameliorates fibrotic kidney disease in mice via inhibiting ACSL4-mediated tubular ferroptosis.Acta pharmacologica Sinica · 2024
- Fisetin: hormesis accounts for many of its chemoprotective effects.Biogerontology · 2025
- Intermittent supplementation with fisetin improves arterial function in old mice by decreasing cellular senescence.Aging cell · 2024
via PubMed
Wikidata facts
Show 6 more facts
- MCN code
- 3203.00.12
- found in taxon
- Acacia carneorum
- chemical formula
- C₁₅H₁₀O₆
- Commons category
- Fisetin
- canonical SMILES
- C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
- has characteristic
- bitterness
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Sources
- Research
- References
Fisetin (7,3′,4′-flavon-3-ol) is a plant flavonol from the flavonoid group of polyphenols. It occurs in many plants where it serves as a yellow pigment. It is found in many fruits and vegetables, such as strawberries, apples, persimmons, onions, and cucumbers.
Its chemical formula was first described by Austrian chemist Josef Herzig in 1891.
Excerpted from Wikipedia’s “fisetin” article, available under the CC BY-SA 4.0 licence.