KANK2
Sign in to saveAlso known as ANKRD25, MXRA3, SIP, PPKWH, KN motif and ankyrin repeat domains 2, NPHS16
KN motif and ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the KANK2 gene.
In the Vinony graph
Within Vinony's link graph, KANK2 is referenced by 1 other article, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KANK2- Name
- KN motif and ankyrin repeat domains 2
- Type
- protein-coding
- Position
- 11,164,264–11,197,945 (−)
- Aliases
- ANKRD25, MXRA3, NPHS16, PPKWH, SIP
- Ensembl
- ENSG00000197256
- RefSeq RNA
- NM_001136191.3, NM_001329451.2, NM_001379548.1, NM_001379549.1, NM_001379550.1
- RefSeq protein
- NP_001129663.1, NP_001316380.1, NP_001366477.1, NP_001366478.1, NP_001366479.1
This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
KN motif and ankyrin repeat domains 2
- Symbol
- KANK2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:11,164,264-11,197,945
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 9163
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25959
- genomic end
- 11308467
- genomic start
- 11274943
- chromosome
- human chromosome 19
- cytogenetic location
- 19p13.2
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
KN motif and ankyrin repeat domain-containing protein 2 is a protein that in humans is encoded by the KANK2 gene.
==References==
Excerpted from Wikipedia’s “KANK2” article, available under the CC BY-SA 4.0 licence.