KIF2A
Sign in to saveAlso known as CDCBM3, HK2, KIF2, kinesin heavy chain member 2A, kinesin family member 2A
Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene. In mice, KIF2A is essential for proper neurogenesis and deficiency of KIF2A in mature neurons results in the loss of those neurons.
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Vinony's link graph records 270 inbound references to KIF2A, and connects out to hair keratin, PubMed and human chromosome 5.
It sits within the topics Genes on human chromosome 5, Human proteins and Motor proteins.
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Gene data
KIF2A- Name
- kinesin family member 2A
- Type
- protein-coding
- Position
- 62,305,974–62,391,025 (+)
- Aliases
- CDCBM3, HK2, KIF2
- Ensembl
- ENSG00000068796
- RefSeq RNA
- NM_001098511.3, NM_001243952.2, NM_001243953.2, NM_004520.5
- RefSeq protein
- NP_001091981.1, NP_001230881.2, NP_001230882.1, NP_004511.2
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
kinesin family member 2A
- Symbol
- KIF2A
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:62,305,974-62,391,025
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein KIF2A PDB 2gry.png
Show 7 more facts
- HomoloGene ID
- 3320
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3796
- genomic end
- 62391025
- genomic start
- 61601989
- chromosome
- human chromosome 5
- cytogenetic location
- 5q12.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene. In mice, KIF2A is essential for proper neurogenesis and deficiency of KIF2A in mature neurons results in the loss of those neurons.
Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM]
Excerpted from Wikipedia’s “KIF2A” article, available under the CC BY-SA 4.0 licence.