thumb|(Left Side) A karyosome with a capsule. (Right Side) A karyosome without a capsule. A karyosome or karyosphere is a dense bundle of chromatin inside the nucleus of a cell within an organism. These bundles are joined together in a limited nuclear volume, but this only happens when the cell is not undergoing meiotic division. Research suggests that within its bundles there is an absence of RNA synthesis occurring in the karyosphere. This suggests that RNA is actively being carried out within meiosis, especially throughout the first and second prophase of meiotic division.
thumb|(Left Side) A karyosome with a capsule. (Right Side) A karyosome without a capsule. A karyosome or karyosphere is a dense bundle of chromatin inside the nucleus of a cell within an organism. These bundles are joined together in a limited nuclear volume, but this only happens when the cell is not undergoing meiotic division. Research suggests that within its bundles there is an absence of RNA synthesis occurring in the karyosphere. This suggests that RNA is actively being carried out within meiosis, especially throughout the first and second prophase of meiotic division.
== Formation and function == Karyosomes are formed in several animal classes and have a role in oogenesis, a vital process in female gamete development. The gametes can only develop if the mother has oocytes, that are rich in cytoplasm, maternal proteins and contain karyosomes.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).