کندومیسین

Kendomycin is an anticancer macrolide first isolated from Streptomyces violaceoruber. It has potent activity as an endothelin receptor antagonist and anti-osteoporosis agent. It also has strong cytotoxicity against various tumor cell lines.

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Within Vinony's link graph, کندومیسین is referenced by 3 other articles, and connects out to Wayback Machine, digital object identifier and chemical formula.

It sits within the topics Antibiotics, Macrolides and Quinone methides.

Its subject is documented across 6 Wikipedia language editions.

Chemical data

Formula: C29H42O6
Molecular weight: 486.6 g/mol
IUPAC name: (1R,9S,10S,12S,14E,16S,19R,20R,21S,22R)-3,9,21-trihydroxy-5,10,12,14,16,20,22-heptamethyl-23,24-dioxatetracyclo[17.3.1.16,9.02,7]tetracosa-2,5,7,14-tetraen-4-one
SMILES: C[C@H]\1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C3=C(C(=O)C(=C4C3=C[C@@](O4)([C@H](C[C@@H](C/C(=C1)/C)C)C)O)C)O)C)O)C
InChIKey: HKLDUJXJTQJSEJ-OLXNOMCWSA-N
XLogP: 4
Polar surface area: 96.2 Å²
H-bond donors: 3
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Mass: 486.298139

Show 3 more facts

chemical formula: C₂₉H₄₂O₆
isomeric SMILES: C[C@H]\1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C3=C(C(=O)C(=C4C3=C[C@@](O4)([C@H](C[C@@H](C/C(=C1)/C)C)C)O)C)O)C)O)C
canonical SMILES: CC1CCC2C(C(C(C(O2)C3=C(C(=O)C(=C4C3=CC(O4)(C(CC(CC(=C1)C)C)C)O)C)O)C)O)C

Sources (1)