File:Osteoclast.jpg · Wikimedia Commons · See Wikimedia Commons
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AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Medical condition.name
- Osteoporosis
- Medical condition.image
- OsteoCutout.png
- Medical condition.alt
- andro
- Medical condition.caption
- Elderly woman with osteoporosis showing a curved back from compression fractures of her back bones.
- Medical condition.field
- Rheumatology, endocrinology, orthopedics
- Medical condition.symptoms
- Increased risk of a broken bone
- Medical condition.complications
- Chronic pain
- Medical condition.onset
- Older age
- Medical condition.risks
- Alcoholism, anorexia nervosa, hyperthyroidism, gastrointestinal diseases, oophorectomy, kidney disease, tobacco smoking, menopausal estradiol loss, certain medications
- Medical condition.diagnosis
- Dexa Scan (bone density scan)
- Medical condition.treatment
- Alcohol and smoking cessation, good diet, exercise, fall prevention
- Medical condition.medication
- Bisphosphonates
- Medical condition.frequency
- 15% (50 year olds), 70% (over 80 year olds)
via Wikipedia infobox
Research
122,350 papers- Postmenopausal Osteoporosis: A Review of Latest Guidelines.ReviewEndocrinology and metabolism clinics of North America · 2024Subarajan P, Arceo-Mendoza RM, Camacho PMDOI: 10.1016/j.ecl.2024.08.008
- Postmenopausal Osteoporosis.ReviewThe New England journal of medicine · 2023Walker MD, Shane EDOI: 10.1056/NEJMcp2307353
- Postmenopausal Osteoporosis: Latest Guidelines.ReviewEndocrinology and metabolism clinics of North America · 2021Arceo-Mendoza RM, Camacho PMDOI: 10.1016/j.ecl.2021.03.009
- T-Cell Mediated Inflammation in Postmenopausal Osteoporosis.ReviewFrontiers in immunology · 2021Wu D, Cline-Smith A, Shashkova E et al.DOI: 10.3389/fimmu.2021.687551
- Long-Term Treatment of Postmenopausal Osteoporosis.Endocrinology and metabolism (Seoul, Korea) · 2021Brown JPDOI: 10.3803/EnM.2021.301
- Interaction between bone and immune cells: Implications for postmenopausal osteoporosis.ReviewSeminars in cell & developmental biology · 2022Fischer V, Haffner-Luntzer MDOI: 10.1016/j.semcdb.2021.05.014
- Estrogen deficiency-mediated osteoimmunity in postmenopausal osteoporosis.ReviewMedicinal research reviews · 2025Yao Y, Cai X, Chen Y et al.DOI: 10.1002/med.22081
- Recent Advances in Osteoporosis Therapeutics.ReviewAnnual review of medicine · 2026Sølling AS, Langdahl BL, Cosman FDOI: 10.1146/annurev-med-050124-040555
via PubMed
~58 min read
Encyclopedic overview
36 sectionsContents
- Signs and symptoms
- Fractures
- Risk of falls
- Complications
- Risk factors
- Non-modifiable
- Potentially modifiable
- Medical disorders
- Medication
- Pregnancy-associated osteoporosis
- Evolutionary
- Fracture risk assessment
- Mechanics
- Pathogenesis
- Diagnosis
- Conventional radiography
- Dual-energy X-ray
- Biomarkers
- Other measuring tools
- Screening
- Prevention
- Nutrition
- Physical exercise
- Physical exercise prescription
- Physical therapy
- Hormone therapy
- Management
- Lifestyle Changes
- Pharmacologic therapy
- Prognosis
- Fractures
- Epidemiology
- History
- See also
- References
- External links
Osteoporosis is a systemic skeletal disorder characterized by low bone mass (osteopenia), micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in fracture risk. Bones undergo continuous remodeling: osteoclasts resorb old bone, and osteoblasts synthesize new bone. With advancing age, the rate of resorption exceeds that of bone formation, causing bones to lose density and become more susceptible to fractures.
It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, the wrist, and the hip.
Excerpted from Wikipedia’s “osteoporosis” article, available under the CC BY-SA 4.0 licence.
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