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osteoporosis

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osteoporosis

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Also known as bone loss

AI overview

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AI-generated from the Wikipedia summary — may contain errors.

Key facts

Medical condition.name
Osteoporosis
Medical condition.image
OsteoCutout.png
Medical condition.alt
andro
Medical condition.caption
Elderly woman with osteoporosis showing a curved back from compression fractures of her back bones.
Medical condition.field
Rheumatology, endocrinology, orthopedics
Medical condition.symptoms
Increased risk of a broken bone
Medical condition.complications
Chronic pain
Medical condition.onset
Older age
Medical condition.risks
Alcoholism, anorexia nervosa, hyperthyroidism, gastrointestinal diseases, oophorectomy, kidney disease, tobacco smoking, menopausal estradiol loss, certain medications
Medical condition.diagnosis
Dexa Scan (bone density scan)
Medical condition.treatment
Alcohol and smoking cessation, good diet, exercise, fall prevention
Medical condition.medication
Bisphosphonates
Medical condition.frequency
15% (50 year olds), 70% (over 80 year olds)

via Wikipedia infobox

Research

122,350 papers

via PubMed

~58 min read

Encyclopedic overview

36 sections
Contents
  • Signs and symptoms
  • Fractures
  • Risk of falls
  • Complications
  • Risk factors
  • Non-modifiable
  • Potentially modifiable
  • Medical disorders
  • Medication
  • Pregnancy-associated osteoporosis
  • Evolutionary
  • Fracture risk assessment
  • Mechanics
  • Pathogenesis
  • Diagnosis
  • Conventional radiography
  • Dual-energy X-ray
  • Biomarkers
  • Other measuring tools
  • Screening
  • Prevention
  • Nutrition
  • Physical exercise
  • Physical exercise prescription
  • Physical therapy
  • Hormone therapy
  • Management
  • Lifestyle Changes
  • Pharmacologic therapy
  • Prognosis
  • Fractures
  • Epidemiology
  • History
  • See also
  • References
  • External links

Osteoporosis is a systemic skeletal disorder characterized by low bone mass (osteopenia), micro-architectural deterioration of bone tissue leading to more porous bone, and consequent increase in fracture risk. Bones undergo continuous remodeling: osteoclasts resorb old bone, and osteoblasts synthesize new bone. With advancing age, the rate of resorption exceeds that of bone formation, causing bones to lose density and become more susceptible to fractures.

It is the most common reason for a broken bone among the elderly. Bones that commonly break include the vertebrae in the spine, the bones of the forearm, the wrist, and the hip.

Excerpted from Wikipedia’s “osteoporosis” article, available under the CC BY-SA 4.0 licence.

Gallery (27)