L-threonine
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form when dissolved in water), a carboxyl group (which is in the deprotonated −COO− form when dissolved in water), and a side chain containing a hydroxyl group, making it a polar, uncharged amino acid. It is essential in humans, meaning the body cannot synthesize it: it must be obtained from the diet. Threonine is synthesized from aspartate in bacteria such as E. coli. It is encoded by all the codons starting AC (ACU, ACC, ACA, and ACG).
AI overview
L-threonine is an amino acid—a building block of proteins—that your body cannot make on its own and must obtain from food. It's important because your body needs it to build and maintain proteins, and it has a special chemical structure that includes a hydroxyl group, making it polar and uncharged.
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Article
12 sectionsContents
- Modifications
- History
- Stereoisomers
- Biosynthesis
- Metabolism
- Metabolic diseases
- Evolutionary significance
- Research of Threonine as a Dietary Supplement in Animals
- Exploration of L-Threonine for Tuberculosis
- Sources
- References
- External links
Threonine (symbol Thr or T) is an amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH form when dissolved in water), a carboxyl group (which is in the deprotonated −COO− form when dissolved in water), and a side chain containing a hydroxyl group, making it a polar, uncharged amino acid. It is essential in humans, meaning the body cannot synthesize it: it must be obtained from the diet. Threonine is synthesized from aspartate in bacteria such as E. coli. It is encoded by all the codons starting AC (ACU, ACC, ACA, and ACG).
Threonine sidechains are often hydrogen bonded; the most common small motifs formed are based on interactions with serine: ST turns, ST motifs (often at the beginning of alpha helices) and ST staples (usually at the middle of alpha helices).
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Alpha-Amino acidsChembox image size setChemical articles having a data pageChemical articles with multiple CAS registry numbersChemical articles with multiple compound IDsChemicals using indexlabelsECHA InfoCard ID from WikidataEssential amino acidsGlucogenic amino acidsGlycine receptor agonistsKetogenic amino acidsProteinogenic amino acids