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leishmaniasis

Also known as leishmaniosis, Post Kala-Azar Dermal Leishmaniasis

Leishmaniasis is a wide array of clinical manifestations caused by protozoal parasites of the Trypanosomatida genus Leishmania. It is generally spread through the bite of phlebotomine sandflies, Phlebotomus and Lutzomyia, and occurs most frequently in the tropics and sub-tropics of Africa, Asia, the Americas, and southern Europe. The disease can present in three main ways: cutaneous, mucocutaneous, or visceral. The cutaneous form presents with skin ulcers, while the mucocutaneous form presents with ulcers of the skin, mouth, and nose. The visceral form starts with skin ulcers and later present

AI overview

Leishmaniasis is a parasitic disease spread through sandfly bites that causes different forms of illness, ranging from skin ulcers to more serious internal infections affecting organs. It primarily affects people in tropical and subtropical regions across Africa, Asia, the Americas, and southern Europe, making it an important public health concern in those parts of the world.

AI-generated from the Wikipedia summary — may contain errors.

Key facts

Medical condition (new).name: Leishmaniasis
Medical condition (new).synonyms: Leishmaniosis
Medical condition (new).image: Skin ulcer due to leishmaniasis, hand of Central American adult 3MG0037 lores.jpg
Medical condition (new).caption: Cutaneous leishmaniasis in the hand of a Central American adult
Medical condition (new).field: Infectious disease
Medical condition (new).pronounce: Leishmaniasis leishmaniosis
Medical condition (new).symptoms: Skin ulcers, fever, low red blood cells, enlarged liver
Medical condition (new).causes: Leishmania parasites spread by sandflies
Medical condition (new).prevention: Bug nets, insecticide
Medical condition (new).frequency: 4–12 million
Medical condition (new).deaths: 24,200 (2015)

via Wikipedia infobox

Research

36,729 papers

Leishmaniasis.ReviewThe New England journal of medicine · 2026Aronson NE, Musa AM, Satoskar ARDOI: 10.1056/NEJMra2403309
Leishmaniasis and various immunotherapeutic approaches.ReviewParasitology · 2018Taslimi Y, Zahedifard F, Rafati SDOI: 10.1017/S003118201600216X
Leishmaniasis in humans: drug or vaccine therapy?ReviewDrug design, development and therapy · 2018Ghorbani M, Farhoudi RDOI: 10.2147/DDDT.S146521
Revolutionizing Leishmaniasis Treatment with Cutting Edge Drug Delivery Systems and Nanovaccines: An Updated Review.ReviewACS infectious diseases · 2024Tambe S, Nag S, Pandya SR et al.DOI: 10.1021/acsinfecdis.4c00010
Visceral leishmaniasis: An overview of vaccine adjuvants and their applications.ReviewVaccine · 2019Ratnapriya S, Keerti, Sahasrabuddhe AA et al.DOI: 10.1016/j.vaccine.2019.04.092
An update on recombinant vaccines against leishmaniasis.ReviewThe Indian journal of medical research · 2024Shital S, Madan E, Selvapandiyan A et al.DOI: 10.25259/IJMR_1040_2024
Peptide Vaccines for Leishmaniasis.ReviewFrontiers in immunology · 2018De Brito RCF, Cardoso JMO, Reis LES et al.DOI: 10.3389/fimmu.2018.01043
NKT cells in leishmaniasis.ReviewImmunobiology · 2017Zamora-Chimal J, Hernández-Ruiz J, Becker IDOI: 10.1016/j.imbio.2016.11.014

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Wikidata facts

Image: Leishmaniasis 100x 1.jpg

Show 4 more facts

Commons category: Leishmaniasis
NCI Thesaurus ID: C34767
exact match: identifiers.org/doid/DOID:9065
ICD-9-CM: 085.9

Sources (9)

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Article

16 sections

Contents

Signs and symptoms
Cause
Vector
Possible non-human reservoirs
Organisms
Risk factors
Diagnosis
Prevention
Treatment
Epidemiology
History
Society and culture
Research
See also
References
External links

Infections in humans are caused by more than 20 species of Leishmania. Risk factors include poverty, malnutrition, deforestation, and urbanization. All three types can be diagnosed by seeing the parasites under microscopy. Additionally, visceral disease can be diagnosed by blood tests.