leukotriene
Sign in to savethumb|right|Leukotriene A4|LTA4 Note the four double bonds, three of them conjugated. This is a common property of A4, B4, C4, D4, and E4. right|thumb|Leukotriene B4|LTB4 thumb|right|Leukotriene C4|LTC4 is a cysteinyl leukotriene, as are D4 and E4. thumb|right|Leukotriene D4|LTD4 thumb|right|Leukotriene E4|LTE4
Research
26,924 papers- Leukotriene receptors.Journal of receptor research · 1989
- Leukotriene A4 hydrolase.Prostaglandins & other lipid mediators · 2002
- Leukotriene C(4) synthase.Prostaglandins, leukotrienes, and essential fatty acids · 2003
- Leukotriene receptors in atherosclerosis.Annals of medicine · 2006
- Structures of Leukotriene Biosynthetic Enzymes and Development of New Therapeutics.Annual review of pharmacology and toxicology · 2023
via PubMed
Article
14 sectionsContents
- History and name
- Types
- Cysteinyl leukotrienes
- LTB<sub>4</sub>
- LTG<sub>4</sub>
- LTB<sub>5</sub>
- Biochemistry
- Function
- Leukotrienes in asthma
- Role of cysteinyl leukotrienes
- See also
- References
- Further reading
- External links
thumb|right|Leukotriene A4|LTA4 Note the four double bonds, three of them conjugated. This is a common property of A4, B4, C4, D4, and E4. right|thumb|Leukotriene B4|LTB4 thumb|right|Leukotriene C4|LTC4 is a cysteinyl leukotriene, as are D4 and E4. thumb|right|Leukotriene D4|LTD4 thumb|right|Leukotriene E4|LTE4
Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase.