inflammation
Sign in to saveInflammation (from ) is part of the biological defence response of body tissues. Inflammatory immunovascular responses can be triggered by a broad range of stimuli, including physical trauma, "dead, damaged, malfunctioning or stressed tissues", pathogens, irritants, toxins, overuse, autoimmunity, allergens, and foreign bodies (e.g. silica and asbestos). The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa).
AI overview
Inflammation is your body's natural defense response when tissues are damaged or threatened by things like injuries, infections, toxins, or allergens. You typically notice it through five main signs: heat, pain, redness, swelling, and loss of function in the affected area.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Medical condition.caption
- An allergic reaction to cefaclor has led to inflammation of the skin on the foot. The cardinal signs of inflammation include: pain, heat, redness, swelling, and loss of function. Some of these indicators can be seen here.
- Medical condition.specialty
- Immunology, rheumatology
- Medical condition.symptoms
- Heat, pain, redness, swelling
- Medical condition.complications
- Asthma, pneumonia, autoimmune diseases
- Medical condition.duration
- Acute: few daysChronic: up to many months, or years
- Medical condition.causes
- Infection, physical injury, autoimmune disorder
- Medical condition.image
- Allergy to Antibiotic Cefaclor.JPG
via Wikipedia infobox
Article
42 sectionsContents
- Signs and symptoms
- Cardinal signs – acute
- Cardinal signs – chronic
- Causes
- Acute and chronic
- Acute
- Acute process
- Chronic
- Vascular component
- Vasodilation and increased permeability
- Plasma cascade systems
- Plasma-derived mediators
- Cellular component
- Leukocyte extravasation
- Phagocytosis
- Cell-derived mediators
- Morphologic patterns
- Disorders
- Atherosclerosis
- Emerging treatments
- Connection to depression
- Allergy
- Myopathies
- Leukocyte defects
- Pharmacological
- Cancer
- Role in cancer
- Mediators and DNA damage in cancer
- HIV and AIDS
- Connection to depression
- Connection to delirium
- Systemic effects
- Acute-phase proteins
- Leukocyte numbers
- Interleukins and obesity
- Outcomes
- Resolution
- Examples
- See also
- Notes
- References
- External links
Inflammation (from ) is part of the biological defence response of body tissues. Inflammatory immunovascular responses can be triggered by a broad range of stimuli, including physical trauma, "dead, damaged, malfunctioning or stressed tissues", pathogens, irritants, toxins, overuse, autoimmunity, allergens, and foreign bodies (e.g. silica and asbestos). The five cardinal signs are heat, pain, redness, swelling, and loss of function (Latin calor, dolor, rubor, tumor, and functio laesa).
Inflammation is a generic response, and therefore is considered a mechanism of innate immunity, not adaptive immunity. It involves immune cells, blood vessels, and molecular mediators. The function of inflammation is to eliminate the initial cause of cell injury, clear out damaged cells and tissues, and initiate tissue repair. Too little inflammation could lead to progressive tissue destruction by the harmful stimulus (e.g. bacteria) and compromise the survival of the organism. However, inflammation can also have negative effects. For instance, too much inflammation, in the form of chronic inflammation, is associated with various diseases, such as hay fever, periodontal disease, atherosclerosis, and osteoarthritis.