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beraprost
Sign in to saveAlso known as MDL 201229, MDL-201229, ML 1229, ML-1229
Beraprost is a pharmaceutical drug used in several Asian countries, including Japan and South Korea, as a vasodilator and antiplatelet agent. It is classified as a prostacyclin analog.
Chemical data
- Formula
- C24H30O5
- Molecular weight
- 398.5 g/mol
- IUPAC name
- 4-[(1R,2R,3aS,8bS)-2-hydroxy-1-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-2,3,3a,8b-tetrahydro-1H-cyclopenta[b][1]benzofuran-5-yl]butanoic acid
via PubChem
Research
575 papers- Beraprost: a review of its pharmacology and therapeutic efficacy in the treatment of peripheral arterial disease and pulmonary arterial hypertension.Drugs · 2002
- Beraprost sodium ameliorates cognitive impairment by promoting oligodendrocyte precursor cell proliferation and differentiation in vascular cognitive impairment mouse model.Neuropharmacology · 2025
- The effects of beraprost sodium on renal function and cardiometabolic profile in patients with diabetes mellitus: a systematic review and meta-analysis of clinical trials.International urology and nephrology · 2022
- Beraprost and Overall Survival in Cats with Chronic Kidney Disease.Veterinary sciences · 2023
- Beraprost ameliorates postmenopausal osteoporosis by regulating Nedd4-induced Runx2 ubiquitination.Cell death & disease · 2021
via PubMed
~2 min read
Encyclopedic overview
3 sectionsContents
- Clinical pharmacology
- Dosage and administration
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 447623508 | IUPAC_name = 4-{(1R,2R,3aS,8bS)-2-Hydroxy-1-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2,3,3a,8b-tetrahydro-1H-benzo[b]cyclopenta[d]furan-5-yl}butanoic acid | image = Beraprost.svg | image_class = skin-invert-image | width = 300
| tradename = Dorner | Drugs.com = | pregnancy_category = | legal_status = | routes_of_administration = Oral
Excerpted from Wikipedia’s “beraprost” article, available under the CC BY-SA 4.0 licence.
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