lymphokine
Sign in to saveAlso known as lymphocyte mediator, lymphokines
Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, including macrophages and other lymphocytes, to an infected site and their subsequent activation to prepare them to mount an immune response. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune respon
Research
137,545 papers- Lymphokine signal transduction.Progress in growth factor research · 1990
- Lymphokine signal transduction.Cellular signalling · 1990
- Heterogeneity in lymphokine profiles of CD4+ and CD8+ T cells and clones activated in vivo and in vitro.Immunological reviews · 1991
- Lymphokine and cytokine production by Fc epsilon RI+ cells.Advances in immunology · 1993
- Lymphokine gene therapy for cancer.Immunology today · 1990
via PubMed
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, including macrophages and other lymphocytes, to an infected site and their subsequent activation to prepare them to mount an immune response. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required. Lymphokines aid B cells to produce antibodies.
Important lymphokines secreted by the T helper cell include: Interleukin 2 Interleukin 3 Interleukin 4 Interleukin 5 Interleukin 6 Granulocyte-macrophage colony-stimulating factor Interferon-gamma
Excerpted from Wikipedia’s “lymphokine” article, available under the CC BY-SA 4.0 licence.