MAP1LC3B

Also known as ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a, microtubule associated protein 1 light chain 3 beta

proteina associata ai microtubuli codificata nell'uomo dal gene MAP1LC3B, ortologo del gene ATG8 dei lievit

Gene data

MAP1LC3B

Name: microtubule associated protein 1 light chain 3 beta
Type: protein-coding
Position: 87,383,953–87,405,090 (+)
Aliases: ATG8F, LC3B, MAP1A/1BLC3, MAP1LC3B-a
Ensembl: ENSG00000140941
RefSeq RNA: NM_022818.5
RefSeq protein: NP_073729.1

The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. [provided by RefSeq, Jul 2008].

Pathways

Ferroptosis - Homo sapiens (human)Macroautophagy Disease Disease Membrane Trafficking Cellular responses to stress Mitophagy PINK1-PRKN Mediated Mitophagy Vesicle-mediated transport Infectious disease

via MyGene.info

Gene · Ensembl

microtubule associated protein 1 light chain 3 beta

Symbol: MAP1LC3B
Biotype: Protein coding
Organism: Homo sapiens
Location: 16:87,383,953-87,405,090
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein MAP1LC3B PDB 1ugm.png

Show 8 more facts

exact match: identifiers.org/ncbigene/81631
found in taxon: Homo sapiens
HomoloGene ID: 69359
chromosome: human chromosome 16
genomic start: 87383953
genomic end: 87438385
cytogenetic location: 16q24.2
expressed in: pons

Sources (4)

via Wikidata · CC0

Article · Italiano

La MAP1LC3B (acronimo di Microtubule-associated proteins 1A/1B light chain 3B), detta più semplicemente LC3, è una proteina associata ai microtubuli codificata nell'uomo dal gene MAP1LC3B, ortologo del gene ATG8 dei lieviti.La LC3 ha un ruolo fondamentale nel processo di autofagia ed in particolare nella formazione della membrana dell'autofagosoma. Secondo altri studi, la LC3 sarebbe coinvolta non tanto nella biogenesi degli autofagosomi, ma soprattutto nella fusione di questi ultimi con i lisosomi.

Abstract from DBpedia / Wikipedia · CC BY-SA