MAP3K13
Sign in to saveAlso known as LZK, MEKK13, MLK, mitogen-activated protein kinase kinase kinase 13
Mitogen-activated protein kinase kinase kinase 13 is an enzyme that in humans is encoded by the MAP3K13 gene.
Gene data
MAP3K13- Name
- mitogen-activated protein kinase kinase kinase 13
- Type
- protein-coding
- Position
- 185,282,941–185,489,094 (+)
- Aliases
- LZK, MEKK13, MLK
- Ensembl
- ENSG00000073803
- RefSeq RNA
- NM_001242314.2, NM_001242317.2, NM_004721.5, NR_038322.2, XM_011513310.3
- RefSeq protein
- NP_001229243.1, NP_001229246.1, NP_004712.1, XP_011511612.1, XP_016862945.1
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mitogen-activated protein kinase kinase kinase 13
- Symbol
- MAP3K13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:185,282,941-185,489,094
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Mitogen-activated protein kinase kinase kinase 13 is an enzyme that in humans is encoded by the MAP3K13 gene.
== Function ==
Excerpted from Wikipedia’s “MAP3K13” article, available under the CC BY-SA 4.0 licence.