GRK6
Sign in to saveAlso known as GPRK6, G protein-coupled receptor kinase 6
This gene encodes a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinase family, and is most highly similar to GRK4 and GRK5. The protein phosphorylates the activated forms of G protein-coupled receptors to regulate their signaling.
Gene data
GRK6- Name
- G protein-coupled receptor kinase 6
- Type
- protein-coding
- Position
- 177,403,204–177,442,901 (+)
- Aliases
- GPRK6
- Ensembl
- ENSG00000198055
- RefSeq RNA
- NM_001004105.3, NM_001004106.3, NM_001364164.2, NM_002082.4, XM_006714858.4
- RefSeq protein
- NP_001004105.1, NP_001004106.1, NP_001351093.1, NP_002073.2, XP_006714921.1
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
G protein-coupled receptor kinase 6
- Symbol
- GRK6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 5:177,403,204-177,442,901
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~3 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
This gene encodes a member of the G protein-coupled receptor kinase subfamily of the Ser/Thr protein kinase family, and is most highly similar to GRK4 and GRK5. The protein phosphorylates the activated forms of G protein-coupled receptors to regulate their signaling.
== Function ==
Excerpted from Wikipedia’s “GRK6” article, available under the CC BY-SA 4.0 licence.