mastocytoma
Sign in to saveAlso known as mast cell neoplasm, Neoplasm of Mast Cells, mast cell tumor, Mast Cell Neoplasm, Tumor of the Mast Cells, Tumor of Mast Cells, Mast cell Proliferative disease
A mastocytoma or mast cell tumor is a type of round-cell tumor consisting of mast cells. It is found in humans and many animal species; the term also can refer to an accumulation or nodule of mast cells that resembles a tumor.
Research
2,215 papers- Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.Current pediatric reviews · 2019
- Grading Cutaneous Mast Cell Tumors in Cats.Veterinary pathology · 2019
- Canine and Feline Cutaneous Mast Cell Tumor: A Comprehensive Review of Treatments and Outcomes.Topics in companion animal medicine · 2020
- Canine oral mucosal mast cell tumours.Veterinary and comparative oncology · 2016
- [Mastocytosis].Annales de dermatologie et de venereologie · 2014
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Wikidata facts
Show 6 more facts
- NCI Thesaurus ID
- C9303
- health specialty
- oncology
- Commons category
- Mastocytoma
- exact match
- identifiers.org/doid/DOID:3664
- ICD-9-CM
- 238.5
- on focus list of Wikimedia project
- WikiProject Medicine
via Wikidata · CC0
~9 min read
Encyclopedic overview
10 sectionsContents
- Signs and symptoms
- Humans
- Animals
- Diagnosis
- Treatment and prognosis
- Other animals
- Dogs
- Cats
- References
- External links
A mastocytoma or mast cell tumor is a type of round-cell tumor consisting of mast cells. It is found in humans and many animal species; the term also can refer to an accumulation or nodule of mast cells that resembles a tumor.
Mast cells originate from the bone marrow and are normally found throughout the connective tissue of the body as normal components of the immune system. As they release histamine, they are associated with allergic reactions. Mast cells also respond to tissue trauma. Mast cell granules contain histamine, heparin, platelet-activating factor, and other substances. Disseminated mastocytosis is rarely seen in young dogs and cats, while mast cell tumors are usually skin tumors in older dogs and cats. Although not always malignant, they do have the potential to be. Up to 25 percent of skin tumors in dogs are mast cell tumors, with a similar number in cats.
Excerpted from Wikipedia’s “mastocytoma” article, available under the CC BY-SA 4.0 licence.