Structure via PubChem · Public domain (PubChem)
medronic acid
Sign in to saveAlso known as methanediylbis(phosphonic acid), methanebisphosphonic acid, methanediphosphonic acid, Methylenediphosphonic acid, Methylene-1,1-bisphosphonic acid, Medronate, Acidum medronicum
chemical compound
Chemical data
- Formula
- CH6O6P2
- Molecular weight
- 176 g/mol
- IUPAC name
- phosphonomethylphosphonic acid
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- chronic kidney disease, postmenopausal osteoporosis, osteogenesis imperfecta
via ChEMBL · EBI
Research
27 papers- Using an In-Sample Addition of Medronic Acid for the Analysis of Purine- and Pyrimidine-Related Derivatives and Its Application in the Study of Lung Adenocarcinoma A549 Cell Lines by LC-MS/MS.Journal of proteome research · 2023
- β,γ-Methylene-ATP and its metabolite medronic acid affect both arterial media calcification and bone mineralization in non-CKD and CKD rats.JBMR plus · 2024
- Synthesis of medronic acid monoesters and their purification by high-performance countercurrent chromatography or by hydroxyapatite.Beilstein journal of organic chemistry · 2016
- Improved LC/MS Methods for the Analysis of Metal-Sensitive Analytes Using Medronic Acid as a Mobile Phase Additive.Analytical chemistry · 2018
- Calcium Medronate-Based Metal-Organic Frameworks as Multifunctional Biomaterials.Crystal growth & design · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 175.964
Show 4 more facts
- chemical formula
- CH₆O₆P₂
- canonical SMILES
- C(P(=O)(O)O)P(=O)(O)O
- World Health Organisation international non-proprietary name
- medronic acid
- melting point
- 203
Sources (2)
via Wikidata · CC0
Gallery (2)
Available in 8 languages
via Wikidata sitelinks · CC0