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methyllysine
Sign in to saveMethyllysine is derivative of the amino acid residue lysine where the sidechain ammonium group has been methylated one or more times.
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Within Vinony's link graph, methyllysine is referenced by 22 other articles, and connects out to deoxyribonucleic acid, biochemistry and amino acid.
Vinony files it under Alpha-Amino acids, Basic amino acids and Diamines.
Its subject is documented across 5 Wikipedia language editions.
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- chemical compound
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- CNCCCCC(N)C(O)=O
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Methyllysine is derivative of the amino acid residue lysine where the sidechain ammonium group has been methylated one or more times.
Such methylated lysines play an important role in epigenetics; the methylation of specific lysines of certain histones in a nucleosome alters the binding of the surrounding DNA to those histones, which in turn affects the expression of genes on that DNA. The binding is affected because the effective radius of the positive charge is increased (methyl groups are larger than the hydrogen atoms they replace), reducing the strongest potential electrostatic attraction with the negatively charged DNA.
Excerpted from Wikipedia’s “methyllysine” article, available under the CC BY-SA 4.0 licence.