nucleosome
Sign in to savethumb|Basic units of chromatin structure
Article
27 sectionsContents
- Structure
- Structure of the core particle
- Overview
- The nucleosome core particle (NCP)
- Protein interactions within the nucleosome
- Histone - DNA interactions
- Histone tail domains
- Higher order structure
- Dynamics
- Nucleosome sliding
- DNA site exposure
- Nucleosome free region
- Modulating nucleosome structure
- Histone post-translational modifications
- Histone variants
- ATP-dependent nucleosome remodeling
- Dynamic nucleosome remodelling across the Yeast genome
- DNA Twist Defects
- Nucleosome assembly ''in vitro''
- Disulfide crosslinked nucleosome core particles
- Nucleosome assembly '' in vivo ''
- H3 and H4
- H2A and H2B
- Gallery
- See also
- References
- External links
thumb|Basic units of chromatin structure
A nucleosome is the basic structural unit of DNA packaging in eukaryotes. The structure of a nucleosome consists of a segment of DNA wound around eight histone proteins and resembles thread wrapped around a spool. The nucleosome is the fundamental subunit of chromatin. Each nucleosome is composed of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4.