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Structure via PubChem · Public domain (PubChem)
metomidate
Sign in to saveMetomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965 and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.
Chemical data
- Formula
- C13H14N2O2
- Molecular weight
- 230.26 g/mol
- IUPAC name
- methyl 3-(1-phenylethyl)imidazole-4-carboxylate
- SMILES
- CC(C1=CC=CC=C1)N2C=NC=C2C(=O)OC
- InChIKey
- FHFZEKYDSVTYLL-UHFFFAOYSA-N
- XLogP
- 2.7
- Polar surface area
- 44.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
181 papers- (11)C-metomidate PET in the diagnosis of adrenal masses and primary aldosteronism: a review of the literature.Endocrine · 2020
- [(11)C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial.Nature medicine · 2023
- Metomidate-based imaging of adrenal masses.Hormones & cancer · 2011
- Lateralization in (11) C-Metomidate PET and outcome of adrenalectomy in primary aldosteronism.Endocrinology, diabetes & metabolism · 2022
- The Role of GABA Receptors in Anesthesia and Sedation: An Updated Review.CNS drugs · 2025
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 230.106
Show 2 more facts
- canonical SMILES
- CC(C1=CC=CC=C1)N2C=NC=C2C(=O)OC
- chemical formula
- C₁₃H₁₄N₂O₂
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Metomidate is a non-barbiturate imidazole that was discovered by Janssen Pharmaceutica in 1965 and under the names (Hypnodil, Nokemyl) is sold as a sedative-hypnotic drug used in Europe to treat humans and for veterinary purposes.
11C-labelled metomidate (11C-metomidate), may be used with positron emission tomography (PET). For instance, to detect tumors of adrenocortical origin.
Excerpted from Wikipedia’s “metomidate” article, available under the CC BY-SA 4.0 licence.