微嵌合體
Sign in to saveAlso known as chimerism
right|thumb|220px|During pregnancy, a two-way traffic of immune cells may occur through the placenta. Exchanged cells can multiply and establish long-lasting cell lines that are immunologically active even decades after giving birth. Microchimerism is the presence of a small number of cells in an individual that have originated from another individual and are therefore genetically distinct. This phenomenon may be related to certain types of autoimmune diseases although the responsible mechanisms are unclear. The term comes from the prefix "micro" + "chimerism" based on the hybrid Chimera of G
Research
8,943 papers- Microchimerism, PERV and Xenotransplantation.Viruses · 2023
- Microchimerism and pregnancy complications with placental dysfunction.Seminars in immunopathology · 2025
- Fetal microchimerism and the two-stage model of preeclampsia.Journal of reproductive immunology · 2023
- Feto-Maternal Microchimerism: The Pre-eclampsia Conundrum.Frontiers in immunology · 2019
- Fetomaternal microchimerism in tissue repair and tumor development.Developmental cell · 2022
via PubMed
Article · 中文
微嵌合體是指有一小部份數量,來自於另一個人、遺傳上與宿主不同的細胞在宿主的身體內殘留。這很可能是一種自體免疫的病,通常見於懷過孕的婦女,又或是她的子女身上發現;亦有可能是病人在接受了器官移植之後,有細胞從移植的器官游離並游走到宿主的身體其他地方。不過,具體的機制到現在還是不太清楚。 懷孕期間,由於母體及胎兒的免疫細胞有機會透過在胎盤進行的血液透析而進行交換,被交換的細胞在宿主內仍有可能會繼續分裂,並在胎兒出生後的數十年後依然留在宿主體內。
Abstract from DBpedia / Wikipedia · CC BY-SA