MNDA
Sign in to saveAlso known as PYHIN3, myeloid cell nuclear differentiation antigen
Myeloid cell Nuclear Differentiation Antigen is a protein that in humans is encoded as MNDA gene.
In the Vinony graph
Vinony's link graph records 812 inbound references to MNDA, and connects out to Q180686, human chromosome 1 and homeobox.
Vinony files it under Genes on human chromosome 1 and Transcription factors.
Vinony links it to 6 Wikipedia language editions.
Gene data
MNDA- Name
- myeloid cell nuclear differentiation antigen
- Type
- protein-coding
- Position
- 158,802,264–158,849,517 (+)
- Aliases
- PYHIN3
- Ensembl
- ENSG00000163563
- RefSeq RNA
- NM_002432.3
- RefSeq protein
- NP_002423.1
The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
myeloid cell nuclear differentiation antigen
- Symbol
- MNDA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:158,802,264-158,849,517
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein MNDA PDB 2dbg.png
Show 5 more facts
- exact match
- identifiers.org/ncbigene/4332
- HomoloGene ID
- 74438
- genomic start
- 158831351
- genomic end
- 158819296
- cytogenetic location
- 1q23.1
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
Myeloid cell Nuclear Differentiation Antigen is a protein that in humans is encoded as MNDA gene.
== Function ==
Excerpted from Wikipedia’s “MNDA” article, available under the CC BY-SA 4.0 licence.