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mucormycosis
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mucormycosis

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Also known as Mucormycosis (disorder), Mucormycosis, unspecified, Zygomycosis (disorder), Zygomycosis [Phycomycosis or Mucormycosis], Zygomycosis, unspecified (disorder), disseminated mucormycosis, zygomycosis, black fungus infection

Mucormycosis, also known as black fungus, is a severe fungal infection that may cause fulminant fungal sinusitis, usually in people who are immunocompromised. It is mostly curable when diagnosed early. Symptoms depend on where in the body the infection occurs. It most commonly infects the nose, sinuses, eyes and brain resulting in a runny nose, one-sided facial swelling and pain, headache, fever, blurred vision, bulging or displacement of the eye (proptosis), and tissue death. Other sites of infection may include the lungs, stomach and intestines, and skin. It tends to progress rapidly and is

Key facts

Medical condition (new).name
Mucormycosis
Medical condition (new).synonyms
Zygomycosis, black fungus
Medical condition (new).image
Zygomycosis.jpg
Medical condition (new).caption
Micrograph of pulmonary mucormycosis
Medical condition (new).field
Clinical Microbiology, Infectious disease, Otorhinolaryngology, Oral and maxillofacial surgery, Emergency medicine
Medical condition (new).symptoms
Depends on location: runny nose, black area of skin, facial swelling, headache, fever, cough, blurred vision
Medical condition (new).complications
Blindness, thrombosis
Medical condition (new).onset
Rapid
Medical condition (new).types
Sinuses and brain, lung, stomach and intestine, skin, disseminated, miscellaneous
Medical condition (new).causes
Fungi of the Mucorales type
Medical condition (new).risks
Diabetes, iron overload, low white cells, cancer, organ transplant, kidney problems, immunosuppressants, long-term steroids
Medical condition (new).diagnosis
Biopsy, culture, medical imaging
Medical condition (new).differential
Orbital cellulitis, cavernous sinus thrombosis, aspergillosis
Medical condition (new).prevention
Face masks, avoiding contact with soil or water-damaged buildings, good diabetic control
Medical condition (new).treatment
Antifungals, surgical debridement, treat underlying medical conditions
Medical condition (new).medication
Amphotericin B, isavuconazole, posaconazole
Medical condition (new).prognosis
Poor
Medical condition (new).frequency
Rare

via Wikipedia infobox

Research

8,063 papers

via PubMed

~23 min read

Encyclopedic overview

27 sections
Contents
  • Classification
  • Signs and symptoms
  • Cause
  • Risk factors
  • Mechanism
  • Diagnosis
  • Imaging
  • Culture and biopsy
  • Other
  • Differential diagnosis
  • Prevention
  • Treatment
  • Medication
  • Surgery
  • Other considerations
  • Prognosis
  • Epidemiology
  • COVID-19–associated mucormycosis
  • Recurrence of mucormycosis during COVID-19 second wave in India
  • History
  • Naming
  • COVID-19–associated mucormycosis
  • Society and culture
  • Other animals
  • References
  • Further reading
  • External links

Mucormycosis, also known as black fungus, is a severe fungal infection that may cause fulminant fungal sinusitis, usually in people who are immunocompromised. It is mostly curable when diagnosed early. Symptoms depend on where in the body the infection occurs. It most commonly infects the nose, sinuses, eyes and brain resulting in a runny nose, one-sided facial swelling and pain, headache, fever, blurred vision, bulging or displacement of the eye (proptosis), and tissue death. Other sites of infection may include the lungs, stomach and intestines, and skin. It tends to progress rapidly and is fatal in about half of sinus cases and almost all cases of the widespread type.

It is spread by spores of molds of the order Mucorales, most often through inhalation, contaminated food, or contamination of open wounds. These fungi are common in soils, decomposing organic matter (such as rotting fruit and vegetables), and animal manure, but usually do not affect people. It is not transmitted between people. Preventive measures include wearing a face mask in dusty areas, avoiding contact with water-damaged buildings, and protecting the skin from exposure to soil such as when gardening or certain outdoor work. Risk factors include diabetes with persistently high blood sugar levels or diabetic ketoacidosis, low white blood cells, cancer, organ transplant, iron overload, kidney problems, long-term steroids or use of immunosuppressants, and to a lesser extent HIV/AIDS.

Excerpted from Wikipedia’s “mucormycosis” article, available under the CC BY-SA 4.0 licence.

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