myofibroblast

Also known as myofibroblasts, myofibroblast cell

A myofibroblast is a cell phenotype that was first described as being in a state between a fibroblast and a smooth muscle cell.

Key facts

Cell.Name: Myofibroblast
Cell.Latin: myofibroblastus
Cell.Image: Testicle-histology-boar.jpg
Cell.Caption: Histological section through testicular parenchyma of a boar. 1 Lumen of tubulus seminiferus contortus, 2 spermatids, 3 spermatocytes, 4 spermatogonia, 5 Sertoli cell, 6 Myofibroblasts, 7 Leydig cells, 8 capillaries

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Research

24,218 papers

Fibroblast and myofibroblast activation in normal tissue repair and fibrosis.Nature reviews. Molecular cell biology · 2024
PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in mice.The Journal of clinical investigation · 2025
The role of the macrophage-to-myofibroblast transition in renal fibrosis.Frontiers in immunology · 2022
Advances in macrophage-myofibroblast transformation in fibrotic diseases.Frontiers in immunology · 2024
Macrophage-to-myofibroblast transition and its role in cardiac fibrosis.International immunopharmacology · 2025

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Wikidata facts

Image: Miofibroblasto1A MET.png

Show 2 more facts

Commons category: Myofibroblast
native label: myofibroblastus

Sources (2)

via Wikidata · CC0

~5 min read

Article

9 sections

Contents

Structure
Location
Markers
Development
Function
Wound healing
See also
References
External links

A myofibroblast is a cell phenotype that was first described as being in a state between a fibroblast and a smooth muscle cell.

== Structure == Myofibroblasts are contractile web-like fusiform cells that are identifiable by their expression of α-smooth muscle actin within their cytoplasmic stress fibers.