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myosin
EntityQ271727· pop 45· linked from 960 articles

Also known as myosins

thumb|Part of the myosin II structure. Atoms in the heavy chain are colored pink (on the left-hand side); atoms in the light chains are colored faded-orange and faded-yellow (also on the left-hand side). Myosins () are a family of motor proteins (though most often protein complexes) best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility.

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Myosins
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~18 min read

Article

30 sections
Contents
  • Structure and functions
  • Domains
  • Power stroke
  • Nomenclature, evolution, and the family tree
  • Myosin classes
  • Myosin I
  • Myosin II
  • Myosin III
  • Myosin IV
  • Myosin V
  • Myosin VI
  • Myosin VII
  • Myosin VIII
  • Myosin IX
  • Myosin X
  • Myosin XI
  • Myosin XII
  • Myosin XIII
  • Myosin XIV
  • Myosin XV
  • Myosin XVI
  • Myosin XVII
  • Myosin XVIII
  • Myosin XIX
  • Genes in humans
  • Paramyosin
  • References
  • Further reading
  • Additional images
  • External links

thumb|Part of the myosin II structure. Atoms in the heavy chain are colored pink (on the left-hand side); atoms in the light chains are colored faded-orange and faded-yellow (also on the left-hand side). Myosins () are a family of motor proteins (though most often protein complexes) best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility.

The first myosin (M2) to be discovered was in 1864 by Wilhelm Kühne. Kühne had extracted a viscous protein from skeletal muscle that he held responsible for keeping the tension state in muscle. He called this protein myosin. The term has been extended to include a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue.

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