myosin
Sign in to savethumb|Part of the myosin II structure. Atoms in the heavy chain are colored pink (on the left-hand side); atoms in the light chains are colored faded-orange and faded-yellow (also on the left-hand side). Myosins () are a family of motor proteins (though most often protein complexes) best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility.
Research
58,539 papers- Myosin Structures.Advances in experimental medicine and biology · 2020
- Myosin XVIII.Advances in experimental medicine and biology · 2020
- Cardiac myosin contraction and mechanotransduction in health and disease.The Journal of biological chemistry · 2021
- Myosin.Annual review of biochemistry · 1984
- Myosin-V: head to tail.Cellular and molecular life sciences : CMLS · 1999
via PubMed
Article
30 sectionsContents
- Structure and functions
- Domains
- Power stroke
- Nomenclature, evolution, and the family tree
- Myosin classes
- Myosin I
- Myosin II
- Myosin III
- Myosin IV
- Myosin V
- Myosin VI
- Myosin VII
- Myosin VIII
- Myosin IX
- Myosin X
- Myosin XI
- Myosin XII
- Myosin XIII
- Myosin XIV
- Myosin XV
- Myosin XVI
- Myosin XVII
- Myosin XVIII
- Myosin XIX
- Genes in humans
- Paramyosin
- References
- Further reading
- Additional images
- External links
thumb|Part of the myosin II structure. Atoms in the heavy chain are colored pink (on the left-hand side); atoms in the light chains are colored faded-orange and faded-yellow (also on the left-hand side). Myosins () are a family of motor proteins (though most often protein complexes) best known for their roles in muscle contraction and in a wide range of other motility processes in eukaryotes. They are ATP-dependent and responsible for actin-based motility.
The first myosin (M2) to be discovered was in 1864 by Wilhelm Kühne. Kühne had extracted a viscous protein from skeletal muscle that he held responsible for keeping the tension state in muscle. He called this protein myosin. The term has been extended to include a group of similar ATPases found in the cells of both striated muscle tissue and smooth muscle tissue.