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N-methyltyramine

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Also known as p-(2-Methylaminoethyl)phenol, 4-Hydroxy-N-methylphenethylamine, Methyl-4-tyramine

'''N-Methyltyramine (NMT), also known as 4-hydroxy-N-methylphenethylamine', is a human trace amine and natural phenethylamine alkaloid found in a variety of plants. As the name implies, it is the N-methyl analog of tyramine, which is a well-known biogenic trace amine with which NMT shares many pharmacological properties. Biosynthetically, NMT is produced by the N-methylation of tyramine via the action of the enzyme phenylethanolamine N-methyltransferase in humans and tyramine N''-methyltransferase in plants.

Key facts

Drug.width2
220px
Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
459828318
Drug.drug_name
N-Methyltyramine
Drug.image
N-Methyltyramine structure.svg
Drug.image_class
skin-invert-image
Drug.width
250px
Drug.image2
N-METHYLTYRAMINE 3d ball and stick.png
Drug.image_class2
bg-transparent
Drug.CAS_number
370-98-9
Drug.PubChem
9727
Drug.ChemSpiderID
9345
Drug.UNII
G3S4E2F7TA
Drug.ChEBI
17458
Drug.synonyms
Methyl-4-tyramine; 4-Hydroxy-N-methylphenethylamine; p-(2-Methylaminoethyl)phenol
Drug.IUPAC_name
4-[2-(methylamino)ethyl]phenol
Drug.C
9

via Wikipedia infobox

~9 min read

Encyclopedic overview

10 sections
Contents
  • Occurrence
  • Chemistry
  • Synthesis
  • Common Salts
  • Basicity
  • Pharmacology
  • Pharmacokinetics
  • Toxicology
  • See also
  • References

'''N-Methyltyramine (NMT), also known as 4-hydroxy-N-methylphenethylamine', is a human trace amine and natural phenethylamine alkaloid found in a variety of plants. As the name implies, it is the N-methyl analog of tyramine, which is a well-known biogenic trace amine with which NMT shares many pharmacological properties. Biosynthetically, NMT is produced by the N-methylation of tyramine via the action of the enzyme phenylethanolamine N-methyltransferase in humans and tyramine N-methyltransferase in plants.

==Occurrence== N-methyltyramine seems to be quite widely distributed in plants.

Excerpted from Wikipedia’s “N-methyltyramine” article, available under the CC BY-SA 4.0 licence.

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