norfenefrine
Sign in to saveAlso known as meta-Octopamine, 3-Octopamine, m-Octopamine
Norfenefrine, also known as '''meta-octopamine or norphenylephrine and sold under the brand name Novadral' among others, is a sympathomimetic medication which is used in the treatment of hypotension (low blood pressure). Along with its structural isomer p''-octopamine and the tyramines, norfenefrine is a naturally occurring endogenous trace amine and plays a role as a minor neurotransmitter in the brain.
Key facts
- Drug.N
- 1
- Drug.O
- 2
- Drug.Verifiedfields
- changed
- Drug.verifiedrevid
- 462263073
- Drug.image
- Norfenefrine.png
- Drug.image_class
- skin-invert-image
- Drug.width
- 200px
- Drug.image2
- (R)-Norfenefrine molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200px
- Drug.alt2
- Ball-and-stick model of (R)-Norfenefrine
- Drug.legal_status
- Rx-only
- Drug.metabolism
- m-Hydroxymandelic acid
- Drug.CAS_number
- 536-21-0
- Drug.CAS_supplemental
- 15308-34-6 (hydrochloride)
- Drug.ATC_prefix
- C01
- Drug.ATC_suffix
- CA05
- Drug.PubChem
- 4538
via Wikipedia infobox
Research
101 papers- Norfenefrine in the treatment of female stress incontinence. A double-blind controlled trial.Urologia internationalis · 1988
- Norfenefrine: haemodynamic effects in healthy volunteers at rest and during orthostasis.European journal of clinical pharmacology · 1983
- Norfenefrine in the treatment of female urinary stress incontinence assessed by one-hour pad weighing test.Urologia internationalis · 1989
- In vivo alpha(1)-adrenergic lipolytic activity in subcutaneous adipose tissue of obese subjects.The Journal of pharmacology and experimental therapeutics · 2002
- Evidence for neuronal uptake and release of norfenefrine and evaluation of its alpha-agonistic effects in the rabbit pulmonary artery.Arzneimittel-Forschung · 1984
via PubMed
~2 min read
Encyclopedic overview
8 sectionsContents
- Medical uses
- Pharmacology
- Pharmacodynamics
- Chemistry
- Society and culture
- Names
- Availability
- References
Norfenefrine, also known as '''meta-octopamine or norphenylephrine and sold under the brand name Novadral' among others, is a sympathomimetic medication which is used in the treatment of hypotension (low blood pressure). Along with its structural isomer p-octopamine and the tyramines, norfenefrine is a naturally occurring endogenous trace amine and plays a role as a minor neurotransmitter in the brain.
==Medical uses== Norfenefrine is used in the treatment of hypotension (low blood pressure). It is said to be similarly effective or less effective than midodrine.
Excerpted from Wikipedia’s “norfenefrine” article, available under the CC BY-SA 4.0 licence.