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benzofuranylpropylaminopentane
Sign in to saveAlso known as (-)-BPAP
(–)-Benzofuranylpropylaminopentane (BPAP; developmental code name FPFS-1169) is an experimental drug related to selegiline which acts as a monoaminergic activity enhancer (MAE). It is orally active in animals.
Chemical data
- Formula
- C16H23NO
- Molecular weight
- 245.36 g/mol
- IUPAC name
- 1-(1-benzofuran-2-yl)-N-propylpentan-2-amine
- SMILES
- CCCC(CC1=CC2=CC=CC=C2O1)NCCC
- InChIKey
- LJHIBIVAYHQPBT-UHFFFAOYSA-N
- XLogP
- 4.4
- Polar surface area
- 25.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 245.177964356
Show 3 more facts
- chemical formula
- C₁₆H₂₃NO
- canonical SMILES
- CCCC(CC1=CC2=CC=CC=C2O1)NCCC
- Commons category
- Benzofuranylpropylaminopentane
via Wikidata · CC0
~10 min read
Encyclopedic overview
11 sectionsContents
- Pharmacology
- Pharmacodynamics
- Monoaminergic activity enhancer
- Other actions
- Pharmacokinetics
- Chemistry
- History
- Research
- See also
- References
- External links
(–)-Benzofuranylpropylaminopentane (BPAP; developmental code name FPFS-1169) is an experimental drug related to selegiline which acts as a monoaminergic activity enhancer (MAE). It is orally active in animals.
BPAP is a highly potent MAE and enhances the nerve impulse propagation-mediated release of serotonin, norepinephrine, and dopamine. At much higher concentrations, BPAP is also a monoamine reuptake inhibitor, specifically of dopamine and norepinephrine and to a much lesser extent of serotonin. BPAP produces psychostimulant-like effects in animals, with these effects mediated by its MAE actions. The drug is a substituted benzofuran derivative and tryptamine relative structurally related to phenylpropylaminopentane (PPAP).
Excerpted from Wikipedia’s “benzofuranylpropylaminopentane” article, available under the CC BY-SA 4.0 licence.