Structure via PubChem · Public domain (PubChem)
Nabilona
Sign in to saveAlso known as LY 109514, LY-109514
Nabilone, sold under the brand name Cesamet among others, is a synthetic cannabinoid with therapeutic use as an antiemetic and as an adjunct analgesic for neuropathic pain. It mimics tetrahydrocannabinol (THC), the primary psychoactive compound found naturally occurring in Cannabis.
In the Vinony graph
Within Vinony's link graph, Nabilona is referenced by 1,419 other articles, and connects out to cannabinoids, tetrahydrocannabinol and antiemetic.
It sits within the topics Analgesics, Antiaggressive drugs and Appetite stimulants.
Its subject is documented across 22 Wikipedia language editions.
Chemical data
- Formula
- C24H36O3
- Molecular weight
- 372.5 g/mol
- IUPAC name
- (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromen-9-one
- SMILES
- CCCCCCC(C)(C)C1=CC(=C2[C@@H]3CC(=O)CC[C@H]3C(OC2=C1)(C)C)O
- InChIKey
- GECBBEABIDMGGL-RTBURBONSA-N
- XLogP
- 6.4
- Polar surface area
- 46.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Wikidata facts
- Instance of
- medication
- Mass
- 372.266445
Show 6 more facts
- subject has role
- anxiolytic
- chemical formula
- C₂₄H₃₆O₃
- Commons category
- Nabilone
- medical condition treated
- vomiting
- canonical SMILES
- CCCCCCC(C)(C)C1=CC2=C(C3CC(=O)CCC3C(O2)(C)C)C(=C1)O
- defined daily dose
- 3
Sources (3)
via Wikidata · CC0
Article · Português
Nabilona, vendido sob a marca Cesamet entre outros, é um canabinóide sintético com uso terapêutico como antiemético e como analgésico auxiliar para dor neuropática. Ele imita o tetraidrocanabinol (THC), o principal composto psicoativo encontrado naturalmente na Cannabis. A Food and Drug Administration (FDA) dos Estados Unidos indicou nabilona para náuseas/vômitos induzidos por quimioterapia. Em outros países, como o Canadá, é amplamente utilizado como terapia adjuvante para o tratamento da dor crônica. Diversos ensaios e estudos de caso demonstraram eficácia modesta no alívio da fibromialgia e da esclerose múltipla.
Abstract from DBpedia / Wikipedia · CC BY-SA