flumizole

Flumizole is an antiinflammatory agent. More specifically, it is a nonsteroidal anti-inflammatory drug (NSAID) that acts via inhibition of the enzyme cyclooxygenase (COX).

In the Vinony graph

Within Vinony's link graph, flumizole is referenced by 215 other articles, and connects out to salicylic acid, metamizole sodium and fenamic acid.

Vinony files it under 4-Methoxyphenyl compounds, Chemical pages without DrugBank identifier and Cyclooxygenase-2 inhibitors.

Its subject is documented across 5 Wikipedia language editions.

Chemical data

Formula: C18H15F3N2O2
Molecular weight: 348.3 g/mol
IUPAC name: 4,5-bis(4-methoxyphenyl)-2-(trifluoromethyl)-1H-imidazole
SMILES: COC1=CC=C(C=C1)C2=C(N=C(N2)C(F)(F)F)C3=CC=C(C=C3)OC
InChIKey: OPYFPDBMMYUPME-UHFFFAOYSA-N
XLogP: 4.2
Polar surface area: 47.1 Å²
H-bond donors: 1
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 348.109

Show 3 more facts

chemical formula: C₁₈H₁₅F₃N₂O₂
canonical SMILES: COC1=CC=C(C=C1)C2=C(N=C(N2)C(F)(F)F)C3=CC=C(C=C3)OC
subject has role: COX-2 inhibitor

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

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Contents

References

Flumizole is an antiinflammatory agent. More specifically, it is a nonsteroidal anti-inflammatory drug (NSAID) that acts via inhibition of the enzyme cyclooxygenase (COX).

== References ==

Excerpted from Wikipedia’s “flumizole” article, available under the CC BY-SA 4.0 licence.