File:Diabetic_glomerulosclerosis_(1)_HE.jpg · Wikimedia Commons · See Wikimedia Commons
nephrotic syndrome
Sign in to saveAlso known as nephrotic syndromes, nephrosis, nefrotický syndrom
Human disease
Key facts
- Specialty
- Nephrology
- Symptoms
- Swelling , weight gain, feeling tired, foamy urine
- Complications
- Blood clots , infections, high blood pressure
- Causes
- Focal segmental glomerulosclerosis , membranous nephropathy , minimal change disease , diabetes , lupus
- Diagnostic method
- Urine testing , kidney biopsy
- Differential diagnosis
- Nephritic syndrome , cirrhosis , severe malnutrition
- Treatment
- Directed at underlying cause
- Frequency
- 5 per 100,000 per year
via Wikipedia infobox
Research
27,981 papers- Nephrotic Syndrome.Primary care · 2020
- Nephrotic Syndrome for the Internist.The Medical clinics of North America · 2023
- Nephrotic syndrome in infants and children: pathophysiology and management.Paediatrics and international child health · 2017
- Childhood idiopathic nephrotic syndrome: recent advancements shaping future guidelines.Pediatric nephrology (Berlin, Germany) · 2025
- Nephrotic Syndrome: Genetics, Mechanism, and Therapies.BioMed research international · 2018
via PubMed
Wikidata facts
- Subclass of
- disease
- Image
- Diabetic glomerulosclerosis (1) HE.jpg
Show 11 more facts
- NCI Thesaurus ID
- C34845
- health specialty
- nephrology
- described by source
- Armenian Soviet Encyclopedia
- drug or therapy used for treatment
- (RS)-cyclophosphamide
- exact match
- purl.obolibrary.org/obo/HP_0000100
- genetic association
- SGPL1
- ICD-9-CM
- 581.9
- on focus list of Wikimedia project
- WikiProject Medicine
- different from
- nephritic syndrome
- symptoms and signs
- hypoalbuminemia
- Commons category
- Nephrotic syndrome
Sources (9)
via Wikidata · CC0
~33 min read
Encyclopedic overview
Nephrotic syndrome is a collection of symptoms due to kidney damage. This includes protein in the urine, low blood albumin levels, high blood lipids, and significant swelling. Other symptoms may include weight gain, feeling tired, and foamy urine. Complications may include blood clots, infections, and high blood pressure.
Causes include a number of kidney diseases such as focal segmental glomerulosclerosis, membranous nephropathy, and minimal change disease. It may also occur as a complication of diabetes, lupus, or amyloidosis. The underlying mechanism typically involves damage to the glomeruli of the kidney. Diagnosis is typically based on urine testing and sometimes a kidney biopsy. It differs from nephritic syndrome in that there are no red blood cells in the urine.
Excerpted from Wikipedia’s “nephrotic syndrome” article, available under the CC BY-SA 4.0 licence.