neutropenia
Sign in to saveAlso known as neutropaenia, neutropenic disorder
Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood. Neutrophils make up the majority of circulating white blood cells and serve as the primary defense against infections by destroying bacteria, bacterial fragments and immunoglobulin-bound viruses in the blood. People with neutropenia are more susceptible to bacterial infections and, without prompt medical attention, the condition may become life-threatening (neutropenic sepsis).
Key facts
- Medical condition (new).name
- Neutropenia
- Medical condition (new).image
- Neutropenia.JPG
- Medical condition (new).caption
- Blood film with a striking absence of neutrophils, leaving only red blood cells and platelets
- Medical condition (new).field
- Infectious disease, Hematology
- Medical condition (new).causes
- Aplastic anemia, Glycogen storage disease, vitamin B12 and folate deficiencies, Cohen syndrome, gene mutations
- Medical condition (new).diagnosis
- CBC
- Medical condition (new).treatment
- Antibiotics, Splenectomy if needed, G-CSF
via Wikipedia infobox
Research
81,552 papers- How I investigate neutropenia.International journal of laboratory hematology · 2020
- [Leukopenia/neutropenia].Therapeutische Umschau. Revue therapeutique · 2006
- Autoimmune neutropenia.Presse medicale (Paris, France : 1983) · 2014
- Neutropenia: Evaluation and Management in the Primary Care Setting.American family physician · 2025
- [Autoimmune neutropenia].La Revue de medecine interne · 2011
via PubMed
Wikidata facts
- Subclass of
- disease
- Image
- Neutropenia.JPG
Show 8 more facts
- health specialty
- hematology
- drug or therapy used for treatment
- filgrastim
- exact match
- identifiers.org/doid/DOID:1227
- Commons category
- Neutropenia
- ICD-9-CM
- 288.0
- genetic association
- ELANE
- on focus list of Wikimedia project
- WikiProject Medicine
- NCI Thesaurus ID
- C80520
Sources (7)
via Wikidata · CC0
~12 min read
Encyclopedic overview
11 sectionsContents
- Signs and symptoms
- Causes
- Pathophysiology
- Diagnosis
- Classification
- Treatment
- Prognosis
- Epidemiology
- See also
- References
- External links
Neutropenia is an abnormally low concentration of neutrophils (a type of white blood cell) in the blood. Neutrophils make up the majority of circulating white blood cells and serve as the primary defense against infections by destroying bacteria, bacterial fragments and immunoglobulin-bound viruses in the blood. People with neutropenia are more susceptible to bacterial infections and, without prompt medical attention, the condition may become life-threatening (neutropenic sepsis).
Neutropenia can be divided into congenital and acquired, with severe congenital neutropenia (SCN) and cyclic neutropenia (CyN) being autosomal dominant and mostly caused by heterozygous mutations in the ELANE gene (neutrophil elastase). Neutropenia can be acute (temporary) or chronic (long lasting). The term is sometimes used interchangeably with "leukopenia" ("deficit in the number of white blood cells").
Excerpted from Wikipedia’s “neutropenia” article, available under the CC BY-SA 4.0 licence.